INT230980

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Context Info
Confidence 0.18
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 6
Disease Relevance 2.15
Pain Relevance 0.41

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (THY1) endoplasmic reticulum (THY1) plasma membrane (THY1)
enzyme binding (THY1) cytoskeleton organization (THY1)
Anatomy Link Frequency
embryonic stem cells 1
THY1 (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 32 87.68 High High
cytokine 45 78.88 Quite High
Inflammation 66 77.28 Quite High
Arthritis 57 63.24 Quite High
Pain 5 45.00 Quite Low
Action potential 6 27.44 Quite Low
Spinal cord 15 24.28 Low Low
Paracetamol 1 22.60 Low Low
fibrosis 5 15.36 Low Low
Inflammatory stimuli 10 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Death 16 93.88 High High
Apoptosis 9 93.44 High High
Aging 9 90.36 High High
Obesity 18 88.08 High High
Hypoxia 35 87.88 High High
Rheumatoid Arthritis 33 87.68 High High
INFLAMMATION 70 77.28 Quite High
Graft Vs Host Disease 7 69.08 Quite High
Bone Cancer 2 67.48 Quite High
Arthritis 59 63.24 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Both MSCs were positive for CD73, CD90, CD105, CD166 and negative for CD34, CD45, CD19 and HLA-DR (Figure 2, Figure S1).
Positive_regulation (positive) of CD90
1) Confidence 0.18 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2814860 Disease Relevance 0.32 Pain Relevance 0.11
CD34 was positive in a subset of CD90-positive cells and nearly all CD34-positive cells also stained for CD90, albeit not brightly (Figure 2c).
Positive_regulation (subset) of CD90
2) Confidence 0.18 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2875643 Disease Relevance 0.20 Pain Relevance 0.06
After 2 passages, when cells are positive for mesenchymal markers (CD105, CD90, CD73, CD166) and negative for hematopoietic/endothelial markers (HLA-Dr, CD34, CD45), we differentiated them with the neurogenic medium as previously described [14].
Positive_regulation (positive) of CD90
3) Confidence 0.15 Published 2008 Journal BMC Genomics Section Body Doc Link PMC2358905 Disease Relevance 0.05 Pain Relevance 0.04
The phenotypic characteristics of the de-ATSC showed significantly increased CD90, CD29, CD44, CD117, and CD133 surface epitope-harboring populations and also they appeared gradually increased embryonic stem cells markers, such as Sox2, SSEA4, and TRA1-80 in the results of FACS and immunocytochemical analysis (Figure 1C and 1D).
Positive_regulation (increased) of CD90 in embryonic stem cells
4) Confidence 0.07 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2817727 Disease Relevance 0.97 Pain Relevance 0
The cells showed no expression of CD45, CD20/CD79a, or HLA-DR, but were positive for CD73, CD90, and CD105 in passage three and six (Table 4).
Positive_regulation (positive) of CD90
5) Confidence 0.07 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2875643 Disease Relevance 0.41 Pain Relevance 0.20
Expanded cells were characterized by FACS analysis and were negative for HLA class1, CD34 and CD45, but were positive for CD44, CD54, CD90 and CD105 (Fig. 1B).
Positive_regulation (positive) of CD90
6) Confidence 0.04 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2722022 Disease Relevance 0.20 Pain Relevance 0

General Comments

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