INT23120

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Context Info
Confidence 0.61
First Reported 1990
Last Reported 2000
Negated 1
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 1.13
Pain Relevance 2.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (CCK) extracellular space (CCK) extracellular region (CCK)
Anatomy Link Frequency
plasma 2
neuron 2
CCK (Homo sapiens)
Pain Link Frequency Relevance Heat
Cholecystokinin 17 100.00 Very High Very High Very High
Chronic pancreatitis 10 99.40 Very High Very High Very High
Pain 1 98.92 Very High Very High Very High
Somatostatin 2 95.72 Very High Very High Very High
Enkephalin 3 88.08 High High
Neuropeptide 5 87.28 High High
Disease Link Frequency Relevance Heat
Pancreatitis 10 99.40 Very High Very High Very High
Pain 1 98.92 Very High Very High Very High
Peripheral Primitive Neuroectodermal Tumors 2 82.28 Quite High
Alcohol Addiction 1 66.20 Quite High
Alcoholic Pancreatitis 1 56.04 Quite High
Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This clonal neuronal cell line provides a unique model system to identify cis- and trans-acting factors responsible for neuron-specific expression and regulation of the CCK gene.
Regulation (responsible) of Regulation (regulation) of CCK in neuron associated with cholecystokinin
1) Confidence 0.61 Published 1990 Journal FEBS Lett. Section Abstract Doc Link 2384178 Disease Relevance 0.16 Pain Relevance 0.64
Somatostatin has been used in many studies in the therapy of pain in chronic pancreatitis and plays a role in the regulation of cholecystokinin levels, however data on its plasma levels are still lacking.
Regulation (role) of Regulation (regulation) of cholecystokinin in plasma associated with pain, cholecystokinin and chronic pancreatitis
2) Confidence 0.44 Published 2000 Journal Hepatogastroenterology Section Abstract Doc Link 10919050 Disease Relevance 0.36 Pain Relevance 0.63
Ethanol did not affect the early phase CCK response to a test meal in any group, but it significantly enhanced the late phase CCK response (40-120 min) in CP patients.
Neg (not) Regulation (affect) of Regulation (response) of CCK associated with chronic pancreatitis and cholecystokinin
3) Confidence 0.24 Published 1996 Journal J. Gastroenterol. Section Abstract Doc Link 8808434 Disease Relevance 0.61 Pain Relevance 0.79

General Comments

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