INT23121

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Context Info
Confidence 0.67
First Reported 1990
Last Reported 2000
Negated 1
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 1.06
Pain Relevance 2.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (GRP) extracellular space (GRP) extracellular region (GRP)
Anatomy Link Frequency
muscle 1
endocrine cells 1
GRP (Homo sapiens)
Pain Link Frequency Relevance Heat
Cholecystokinin 14 100.00 Very High Very High Very High
Neuropeptide 11 100.00 Very High Very High Very High
Enkephalin 17 99.76 Very High Very High Very High
Serotonin 1 98.60 Very High Very High Very High
Somatostatin 1 98.16 Very High Very High Very High
substance P 6 90.36 High High
abdominal pain 1 79.92 Quite High
Disease Link Frequency Relevance Heat
Cyst 7 99.74 Very High Very High Very High
Peripheral Primitive Neuroectodermal Tumors 4 99.56 Very High Very High Very High
Abdominal Pain 1 79.92 Quite High
Congenital Anomalies 1 75.00 Quite High
Diverticulum 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The immunohistochemical study showed that endocrine cells were present within the cyst epithelium, positive for chromogranin, synaptophysin, bombesin, and calcitonin, and negative for serotonin, somatostatin, glucagon, insulin, gastrin, and pancreatic polypeptide.
Neg (negative) Transcription (positive) of bombesin in endocrine cells associated with somatostatin, cyst and serotonin
1) Confidence 0.67 Published 2000 Journal Hum. Pathol. Section Abstract Doc Link 10685641 Disease Relevance 0.71 Pain Relevance 0.18
The cholinergic human neuroepithelioma cell line SK-N-MCIXC expressed mRNAs for the neuropeptides cholecystokinin (CCK), neuropeptide Y, gastrin-releasing peptide (GRP) and enkephalin.
Transcription (expressed) of GRP associated with peripheral primitive neuroectodermal tumors, neuropeptide, enkephalin and cholecystokinin
2) Confidence 0.52 Published 1990 Journal FEBS Lett. Section Abstract Doc Link 2384178 Disease Relevance 0.17 Pain Relevance 0.65
The cholinergic human neuroepithelioma cell line SK-N-MCIXC expressed mRNAs for the neuropeptides cholecystokinin (CCK), neuropeptide Y, gastrin-releasing peptide (GRP) and enkephalin.
Transcription (expressed) of gastrin-releasing peptide associated with peripheral primitive neuroectodermal tumors, neuropeptide, enkephalin and cholecystokinin
3) Confidence 0.52 Published 1990 Journal FEBS Lett. Section Abstract Doc Link 2384178 Disease Relevance 0.17 Pain Relevance 0.65
GRP immunoreactivity was detected in 46 and 38% of the DiI-labelled muscle and mucosa neurones, respectively.
Transcription (detected) of GRP in muscle
4) Confidence 0.40 Published 2000 Journal J. Chem. Neuroanat. Section Abstract Doc Link 10936745 Disease Relevance 0 Pain Relevance 0.90

General Comments

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