INT231217

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Context Info
Confidence 0.26
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.67
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (ANK2) signal transduction (ANK2) plasma membrane (ANK2)
cytoskeleton (ANK2) cytoplasm (ANK2)
ANK2 (Homo sapiens)
Pain Link Frequency Relevance Heat
potassium channel 3 73.76 Quite High
beta blocker 3 62.04 Quite High
Action potential 4 60.64 Quite High
sodium channel 7 5.00 Very Low Very Low Very Low
Calcium channel 3 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Angina 1 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
Inward rectifier potassium channel 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Syndrome 37 86.52 High High
Andersen Syndrome 6 80.12 Quite High
Disease 17 79.36 Quite High
Deafness 2 73.88 Quite High
Stress 3 47.72 Quite Low
Sudden Death 6 41.12 Quite Low
Syncope 3 40.48 Quite Low
Arrhythmogenic Right Ventricular Dysplasia 8 10.76 Low Low
Channelopathies 2 7.56 Low Low
Hypertrophic Cardiomyopathy 41 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
LQT4 is caused by mutations in the ANK2 genes that encodes an intracellular protein called Ankyrin B that is involved in ion channels anchoring to the cellular membrane [10].
Positive_regulation (caused) of LQT4
1) Confidence 0.26 Published 2008 Journal Indian Pacing and Electrophysiology Journal Section Body Doc Link PMC2363724 Disease Relevance 0.67 Pain Relevance 0.12

General Comments

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