INT231220

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Context Info
Confidence 0.40
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.91
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (ANK2) signal transduction (ANK2) plasma membrane (ANK2)
cytoskeleton (ANK2) cytoplasm (ANK2)
Anatomy Link Frequency
reticulum 1
ANK2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Calcium channel 3 98.76 Very High Very High Very High
sodium channel 7 98.08 Very High Very High Very High
beta blocker 3 85.52 High High
potassium channel 3 18.16 Low Low
Action potential 4 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Angina 1 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
Inward rectifier potassium channel 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Arrhythmias 2 Under Development 5 95.44 Very High Very High Very High
Heart Rate Under Development 7 94.16 High High
Adhesions 2 92.52 High High
Syndrome 37 89.64 High High
Malignant Neoplastic Disease 3 83.60 Quite High
Arrhythmia Under Development 3 64.48 Quite High
Andersen Syndrome 6 52.48 Quite High
Disease 17 52.36 Quite High
Congenital Anomalies 2 43.04 Quite Low
Hypertrophic Cardiomyopathy 41 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
ANK2 encodes for an intracellular protein (Ankyrin B) that regulates the proper intracellular localization of plasmalemmal ion channels (calcium channel, sodium channel, sodium/calcium exchanger), sarcoplasmic reticulum channels (ryanodine receptor, inositol triphosphate receptor), and other adhesion molecules.
Localization (localization) of Ankyrin B in reticulum associated with calcium channel, sodium channel and adhesions
1) Confidence 0.40 Published 2008 Journal Indian Pacing and Electrophysiology Journal Section Body Doc Link PMC2363724 Disease Relevance 0.91 Pain Relevance 0.17

General Comments

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