INT231258

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Context Info
Confidence 0.23
First Reported 2008
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.16
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Erbb4) mitochondrion (Erbb4) plasma membrane (Erbb4)
nucleus (Erbb4) kinase activity (Erbb4) cytoplasm (Erbb4)
Anatomy Link Frequency
dorsal telencephalon 1
Erbb4 (Mus musculus)
Pain Link Frequency Relevance Heat
interneuron 1 85.92 High High
imagery 3 78.64 Quite High
cerebral cortex 5 5.36 Low Low
Nicotine 12 5.00 Very Low Very Low Very Low
Kinase C 6 5.00 Very Low Very Low Very Low
Neurotransmitter 4 5.00 Very Low Very Low Very Low
Somatosensory cortex 4 5.00 Very Low Very Low Very Low
gABA 3 5.00 Very Low Very Low Very Low
Glutamate 3 5.00 Very Low Very Low Very Low
Hippocampus 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 38 87.76 High High
Apoptosis 2 74.80 Quite High
Neurodegenerative Disease 8 26.48 Quite Low
Disseminated Intravascular Coagulation 10 5.00 Very Low Very Low Very Low
Targeted Disruption 9 5.00 Very Low Very Low Very Low
Malformations Of Cortical Development 7 5.00 Very Low Very Low Very Low
Schizophrenia 6 5.00 Very Low Very Low Very Low
Syndrome 6 5.00 Very Low Very Low Very Low
Alzheimer's Dementia 5 5.00 Very Low Very Low Very Low
Congenital Anomalies 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In this study we demonstrate that Type III Nrg1, acting as a receptor for ErbB4, controls the insertion of ?
ErbB4 Binding (receptor) of
1) Confidence 0.23 Published 2008 Journal The Journal of Cell Biology Section Body Doc Link PMC2364689 Disease Relevance 0 Pain Relevance 0
For example, the ErbB4 ICD has been found to bind to astrocytic gene promoters to suppress their expression [126].
ErbB4 Binding (bind) of
2) Confidence 0.22 Published 2011 Journal Mol Brain Section Body Doc Link PMC3022812 Disease Relevance 0.16 Pain Relevance 0
Others report that interneurons born in the ganglionic eminences express erbB4 and tangential migration toward the dorsal telencephalon is partially controlled by NRG1 via erbB4 [64], [65].
erbB4 Binding (migration) of in dorsal telencephalon
3) Confidence 0.05 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2965671 Disease Relevance 0 Pain Relevance 0.08

General Comments

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