INT231261

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.31
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.32
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (Nrg1) extracellular space (Nrg1) cell morphogenesis (Nrg1)
plasma membrane (Nrg1) cytoplasm (Nrg1)
Anatomy Link Frequency
glial cell 1
Nrg1 (Mus musculus)
Pain Link Frequency Relevance Heat
Demyelination 10 99.64 Very High Very High Very High
Neurotransmitter 4 88.68 High High
unmyelinated 7 55.68 Quite High
hypoalgesia 4 50.00 Quite Low
ischemia 5 16.64 Low Low
Nicotine 12 5.00 Very Low Very Low Very Low
Inflammation 11 5.00 Very Low Very Low Very Low
Central nervous system 6 5.00 Very Low Very Low Very Low
Peripheral nervous system 5 5.00 Very Low Very Low Very Low
imagery 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Demyelinating Disease 10 99.64 Very High Very High Very High
Injury 4 99.38 Very High Very High Very High
Stress 33 99.10 Very High Very High Very High
Cognitive Disorder 13 86.88 High High
Alzheimer's Dementia 23 85.32 High High
Shock 7 73.16 Quite High
Increased Venous Pressure Under Development 5 72.32 Quite High
Death 22 69.96 Quite High
Apoptosis 14 66.00 Quite High
Disease 155 61.56 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
On the other hand, KU-32 was ineffective in preventing NRG1-induced demyelination in co-cultures prepared from Hsp70 KO mice (Figures 3D–3F).
Regulation (ineffective) of NRG1 associated with demyelination
1) Confidence 0.31 Published 2010 Journal ASN NEURO Section Body Doc Link PMC2919983 Disease Relevance 0.30 Pain Relevance 0.10
Presynaptic Type III Neuregulin1-ErbB signaling targets ?
Regulation (targets) of Neuregulin1
2) Confidence 0.27 Published 2008 Journal The Journal of Cell Biology Section Title Doc Link PMC2364689 Disease Relevance 0 Pain Relevance 0.04
Not only are several recently identified BACE1 substrates involved in the response to stress and/or injury such as axonal growth and the regulation of glial cell survival (NRG1; [251]), recovery from excitotoxicity (A?
Regulation (regulation) of NRG1 in glial cell associated with stress and injury
3) Confidence 0.13 Published 2007 Journal Current Genomics Section Body Doc Link PMC2647160 Disease Relevance 1.02 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox