INT231290

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Context Info
Confidence 0.03
First Reported 2008
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.71
Pain Relevance 0.68

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Helt) nucleus (Helt) DNA binding (Helt)
Anatomy Link Frequency
neurons 5
glial cells 1
Helt (Mus musculus)
Pain Link Frequency Relevance Heat
Anterior cingulate cortex 64 99.68 Very High Very High Very High
Glutamate 29 99.58 Very High Very High Very High
nMDA receptor 6 97.04 Very High Very High Very High
imagery 18 47.84 Quite Low
Neuronal excitability 10 28.32 Quite Low
positron emission tomography 3 14.28 Low Low
Limbic system 1 9.76 Low Low
Pyramidal cell 13 5.00 Very Low Very Low Very Low
tetrodotoxin 12 5.00 Very Low Very Low Very Low
Hippocampus 10 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Toxicity 8 97.80 Very High Very High Very High
Disease Progression 4 84.76 Quite High
Death 26 82.80 Quite High
Prion Diseases 12 80.48 Quite High
Scrapie 6 75.36 Quite High
Targeted Disruption 28 75.12 Quite High
Infection 2 70.48 Quite High
Hypoactive Sexual Desire Disorder 1 52.16 Quite High
Stroke 8 43.44 Quite Low
Convulsion 8 26.36 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, it is likely that the accumulation of PrPSc aggregates on neurons and glial cells (Rezaie and Lantos, 2001) results in enhanced glutamate levels in the diseased brain as caused by cell damage.
Positive_regulation (results) of Positive_regulation (accumulation) of neurons in neurons associated with glutamate
1) Confidence 0.03 Published 2008 Journal The Journal of Cell Biology Section Body Doc Link PMC2364707 Disease Relevance 0.83 Pain Relevance 0.10
We propose that the increased presynaptic glutamate release is the main trigger for the activation of neurons in the ACC following sexual attraction.
Positive_regulation (trigger) of Positive_regulation (activation) of neurons in neurons associated with glutamate and anterior cingulate cortex
2) Confidence 0.01 Published 2009 Journal Mol Brain Section Body Doc Link PMC2685783 Disease Relevance 0.05 Pain Relevance 0.49
However, it is likely that the accumulation of PrPSc aggregates on neurons and glial cells (Rezaie and Lantos, 2001) results in enhanced glutamate levels in the diseased brain as caused by cell damage.
Positive_regulation (results) of in glial cells Positive_regulation (accumulation) of neurons in neurons associated with glutamate
3) Confidence 0.01 Published 2008 Journal The Journal of Cell Biology Section Body Doc Link PMC2364707 Disease Relevance 0.83 Pain Relevance 0.10

General Comments

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