INT231301

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Context Info
Confidence 0.26
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.24
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Prnp, Grin1) cytoplasm (Prnp, Grin1) transport (Grin1)
Golgi apparatus (Prnp) endoplasmic reticulum (Prnp) nucleolus (Prnp)
Prnp (Mus musculus)
Grin1 (Mus musculus)
Pain Link Frequency Relevance Heat
Glutamate 9 81.44 Quite High
tetrodotoxin 6 5.00 Very Low Very Low Very Low
imagery 6 5.00 Very Low Very Low Very Low
Neuronal excitability 5 5.00 Very Low Very Low Very Low
Hippocampus 5 5.00 Very Low Very Low Very Low
GABAergic 4 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
agonist 3 5.00 Very Low Very Low Very Low
hyperexcitability 2 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Toxicity 4 91.04 High High
Death 13 69.28 Quite High
Convulsion 4 31.60 Quite Low
Stroke 4 18.24 Low Low
Targeted Disruption 10 5.00 Very Low Very Low Very Low
Prion Diseases 6 5.00 Very Low Very Low Very Low
Myelodysplastic Syndromes 3 5.00 Very Low Very Low Very Low
Scrapie 3 5.00 Very Low Very Low Very Low
Disease 3 5.00 Very Low Very Low Very Low
Sprains And Strains 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, irrespective of the molecular mechanisms underlying the observed effects, our data support a major role of PrPC in regulating NMDAR function.
PrPC Regulation (role) of Regulation (regulating) of NMDAR
1) Confidence 0.26 Published 2008 Journal The Journal of Cell Biology Section Body Doc Link PMC2364707 Disease Relevance 0.24 Pain Relevance 0.08

General Comments

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