INT231341

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Context Info
Confidence 0.12
First Reported 1996
Last Reported 2011
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.21
Pain Relevance 0.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Got1) biosynthetic process (Got1) cellular amino acid metabolic process (Got1)
lysosome (Got1) cytoplasm (Got1)
Got1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
fibrosis 2 96.24 Very High Very High Very High
Inflammation 11 86.96 High High
Inflammatory mediators 2 64.64 Quite High
Arthritis 1 57.96 Quite High
neuralgia 1 57.40 Quite High
Glutamate 2 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cirrhosis 2 99.20 Very High Very High Very High
Occupational Lung Diseases 1 89.08 High High
INFLAMMATION 13 86.96 High High
Fibrosis 1 83.64 Quite High
Disease 1 75.00 Quite High
Myocardial Infarction 9 69.56 Quite High
Arthritis 1 57.96 Quite High
Neuralgia 1 57.40 Quite High
Malignant Neoplastic Disease 1 52.72 Quite High
Autoimmune Disease 1 52.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
mg/kg doses of F2, resp.) showed significant decrease (P < .001) in ISO-affected levels of CK-MB, LDH, GOT, ALK-P, and uric acid in a dose-dependent manner compared to Group II (vehicle-treated group injected with ISO), while Group VI (administered with 50?
Negative_regulation (decrease) of Gene_expression (levels) of GOT
1) Confidence 0.12 Published 2011 Journal Evidence-based Complementary and Alternative Medicine : eCAM Section Body Doc Link PMC2952329 Disease Relevance 0.14 Pain Relevance 0
Moore reduced the levels of serum GOT and GPT in the rat cirrhosis model induced by CCL4, and it was effective in reducing hepatic fibrosis and nodular formation.
Negative_regulation (reduced) of Gene_expression (levels) of serum GOT associated with fibrosis and cirrhosis
2) Confidence 0.01 Published 1996 Journal Mediators Inflamm Section Abstract Doc Link PMC2365809 Disease Relevance 1.08 Pain Relevance 0.38

General Comments

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