INT231379

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Context Info
Confidence 0.26
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.72
Pain Relevance 1.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Pmp22) cell cycle (Pmp22)
Anatomy Link Frequency
dorsal root 2
Pmp22 (Mus musculus)
Pain Link Frequency Relevance Heat
Demyelination 28 99.64 Very High Very High Very High
Peripheral nerve injury 4 98.20 Very High Very High Very High
allodynia 20 97.04 Very High Very High Very High
dorsal root ganglion 7 92.52 High High
Neuropathic pain 52 89.12 High High
Spinal cord 11 76.76 Quite High
Sciatic nerve 11 71.12 Quite High
Thermal hyperalgesia 3 54.96 Quite High
c fibre 24 16.60 Low Low
Pain 34 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Demyelinating Disease 31 99.64 Very High Very High Very High
Nervous System Injury 28 97.76 Very High Very High Very High
Neuropathic Pain 79 97.04 Very High Very High Very High
Ganglion Cysts 8 92.52 High High
Hyperalgesia 10 54.96 Quite High
Nociception 28 39.68 Quite Low
Injury 15 30.48 Quite Low
Pain 42 5.00 Very Low Very Low Very Low
Targeted Disruption 5 5.00 Very Low Very Low Very Low
Disease 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, LPA1 receptor-mediated demyelination was evidenced by down-regulation of myelin-associated proteins, such as MBP and peripheral myelin protein 22 kDa (PMP22), in the dorsal root after LPA injection or peripheral nerve injury.
Negative_regulation (down) of Negative_regulation (regulation) of PMP22 in dorsal root associated with demyelination, nervous system injury and peripheral nerve injury
1) Confidence 0.26 Published 2008 Journal Mol Pain Section Body Doc Link PMC2365930 Disease Relevance 1.72 Pain Relevance 1.09

General Comments

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