INT231433

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Context Info
Confidence 0.34
First Reported 2007
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.60
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IGFBP3) extracellular region (IGFBP3) nucleus (IGFBP3)
Anatomy Link Frequency
molar 2
IGFBP3 (Homo sapiens)
Pain Link Frequency Relevance Heat
tolerance 7 71.08 Quite High
Inflammation 6 8.16 Low Low
Somatostatin 17 5.00 Very Low Very Low Very Low
imagery 12 5.00 Very Low Very Low Very Low
headache 7 5.00 Very Low Very Low Very Low
Pain 5 5.00 Very Low Very Low Very Low
carpal tunnel syndrome 4 5.00 Very Low Very Low Very Low
Dopamine 3 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Acromegaly 83 99.28 Very High Very High Very High
Impaired Glucose Tolerance 8 71.08 Quite High
Renal Disease 5 48.08 Quite Low
Body Weight 1 42.52 Quite Low
Chronic Renal Failure 43 23.12 Low Low
INFLAMMATION 6 8.16 Low Low
Necrosis 1 6.96 Low Low
Disease 18 6.48 Low Low
Pituitary Cancer 18 5.84 Low Low
Cancer 37 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The concentration of IGFBP3, the main IGF carrier protein, is usually increased in patients with acromegaly, but this marker offers little further diagnostic information.


Positive_regulation (increased) of IGFBP3 Binding (concentration) of associated with acromegaly
1) Confidence 0.34 Published 2008 Journal Orphanet J Rare Dis Section Body Doc Link PMC2459162 Disease Relevance 0.60 Pain Relevance 0.04
The molar ratio for IGF-I/IGFBP-III was also calculated using the following equation:

(IGF-I/7·5)/(IGFBP-III/30·5)

Positive_regulation (calculated) of IGFBP-III Binding (ratio) of in molar
2) Confidence 0.07 Published 2007 Journal Clinical Endocrinology Section Body Doc Link PMC2366021 Disease Relevance 0 Pain Relevance 0

General Comments

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