INT231528

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Context Info
Confidence 0.73
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.78
Pain Relevance 1.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (NT5C3) mitochondrion (NT5C3) small molecule metabolic process (NT5C3)
endoplasmic reticulum (NT5C3) cytoplasm (NT5C3)
Anatomy Link Frequency
dorsal horn 1
NT5C3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Dorsal horn 4 98.16 Very High Very High Very High
antinociception 1 95.36 Very High Very High Very High
gABA 2 94.48 High High
Action potential 1 93.28 High High
Pain threshold 1 92.12 High High
agonist 24 90.80 High High
mu opioid receptor 1 90.48 High High
Spinal cord 8 85.88 High High
Lasting pain 1 83.68 Quite High
Acute pain 1 82.60 Quite High
Disease Link Frequency Relevance Heat
Rhabdomyosarcoma 112 95.28 Very High Very High Very High
Pain 6 92.12 High High
Cancer 84 85.44 High High
Targeted Disruption 10 78.48 Quite High
Anaplasia 1 69.04 Quite High
Leiomyosarcoma 2 66.68 Quite High
Rhinitis 2 61.52 Quite High
Sclerosis 2 60.32 Quite High
Nociception 3 40.64 Quite Low
Urological Neuroanatomy 2 27.32 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Electrical stimulation of the PVN or oxytocin application caused the activation of presynaptic oxytocin receptors at the terminals of glutamatergic interneurones, which, in turn, activated local GABA neurones to suppress the action potential firing of the laminar II dorsal horn neurones induced by inputs from A-?
Localization (application) of PVN in dorsal horn associated with action potential, gaba and dorsal horn
1) Confidence 0.73 Published 2010 Journal CNS Neuroscience & Therapeutics Section Body Doc Link PMC2972642 Disease Relevance 0.41 Pain Relevance 1.06
In about 22% a t(1;13)(p36;q14) translocation is found with fusion transcript PAX7-FKHR.
Localization (translocation) of p36
2) Confidence 0.18 Published 2008 Journal Pediatr Radiol Section Body Doc Link PMC2367394 Disease Relevance 1.37 Pain Relevance 0

General Comments

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