INT231559

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Context Info
Confidence 0.06
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.36
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (STAT1) nucleoplasm (STAT1) nucleolus (STAT1)
nucleus (STAT1) enzyme binding (STAT1) cytoplasm (STAT1)
STAT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 31 81.64 Quite High
cytokine 10 65.28 Quite High
chemokine 4 63.84 Quite High
cINOD 7 39.92 Quite Low
Inflammation 23 5.00 Very Low Very Low Very Low
Multiple sclerosis 8 5.00 Very Low Very Low Very Low
antagonist 6 5.00 Very Low Very Low Very Low
Glutamate 6 5.00 Very Low Very Low Very Low
Kinase C 2 5.00 Very Low Very Low Very Low
Neuritis 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypopituitarism 11 75.36 Quite High
Cataract 4 61.08 Quite High
Targeted Disruption 10 56.96 Quite High
Reprotox - General 3 1 55.08 Quite High
Frailty 4 54.16 Quite High
Myotonic Dystrophy 8 50.00 Quite Low
Death 5 50.00 Quite Low
Drug Induced Neurotoxicity 1 36.24 Quite Low
Alzheimer's Dementia 3 32.48 Quite Low
Neurological Disease 1 23.60 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
B binding activity although it decreased STAT-1 expression and enhanced expression and binding activity of the AP-1 proteins
Negative_regulation (decreased) of Gene_expression (expression) of STAT-1
1) Confidence 0.06 Published 2008 Journal PPAR Research Section Body Doc Link PMC2367430 Disease Relevance 0 Pain Relevance 0.14
Measured fractions of Specificity protein 1 (Sp1), Signal Transducer and Activator of Transcription (STAT1 and STAT3) and Retinoic Acid Receptor gamma (RAR?)
Negative_regulation (Measured) of Gene_expression (fractions) of Signal Transducer and Activator
2) Confidence 0.02 Published 2008 Journal Current Genomics Section Body Doc Link PMC2694559 Disease Relevance 0.36 Pain Relevance 0

General Comments

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