INT231574

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Context Info
Confidence 0.04
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.35
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (TAB2) plasma membrane (TAB2) intracellular (TAB2)
cytoplasm (TAB2)
TAB2 (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 38 83.36 Quite High
alcohol 1 74.16 Quite High
Inflammation 30 5.00 Very Low Very Low Very Low
Arthritis 3 5.00 Very Low Very Low Very Low
Neuropathic pain 1 5.00 Very Low Very Low Very Low
depression 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Rheumatism 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 41 83.36 Quite High
Disease 15 72.44 Quite High
Breast Cancer 24 50.96 Quite High
Cancer 80 5.00 Very Low Very Low Very Low
INFLAMMATION 30 5.00 Very Low Very Low Very Low
Metastasis 3 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low
Stress 2 5.00 Very Low Very Low Very Low
Apoptosis 2 5.00 Very Low Very Low Very Low
Malignant Neoplastic Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The three most important SNPs for the prediction were PTPN22*rs2476601, MAP3K71P2*rs577001, and RUNX1*rs2268277.
MAP3K71P2 Binding (rs2476601) of
1) Confidence 0.04 Published 2007 Journal BMC Proc Section Body Doc Link PMC2367463 Disease Relevance 0.29 Pain Relevance 0.11
The HercepTest (DAKO) is directed against the intracellular region of ERBB2 with high sensitivity; TAB250 anti-ERBB2 recognizes with high specificity but low sensitivity the extracellular region of the receptor [10].
TAB250 Binding (recognizes) of
2) Confidence 0.00 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2958950 Disease Relevance 0.05 Pain Relevance 0.04

General Comments

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