INT231587

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Context Info
Confidence 0.16
First Reported 2008
Last Reported 2010
Negated 2
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 1.10
Pain Relevance 0.93

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (SBDS) nucleoplasm (SBDS) nucleolus (SBDS)
rRNA binding (SBDS) cytoskeleton (SBDS) nucleus (SBDS)
Anatomy Link Frequency
insular cortex 1
basal ganglia 1
thalamus 1
cerebellum 1
SBDS (Homo sapiens)
Pain Link Frequency Relevance Heat
Thalamus 69 96.98 Very High Very High Very High
Somatosensory cortex 163 94.96 High High
Substantia nigra 15 89.44 High High
medulla 9 87.84 High High
antagonist 3 83.80 Quite High
positron emission tomography 3 73.64 Quite High
drug abuse 2 67.44 Quite High
tetrodotoxin 3 65.92 Quite High
cerebral cortex 3 53.04 Quite High
Potency 1 41.44 Quite Low
Disease Link Frequency Relevance Heat
Adrenal Cancer 91 92.88 High High
Epilepsy 45 90.12 High High
Convulsion 48 81.72 Quite High
Absence Epilepsy 36 71.88 Quite High
Drug Dependence 3 67.44 Quite High
Increased Venous Pressure Under Development 18 67.40 Quite High
Manic Depressive Disorder 2 66.76 Quite High
Virilism 3 65.56 Quite High
Syndrome 2 65.48 Quite High
Cognitive Disorder 6 18.76 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Whereas, to our knowledge, the role of the cerebellum in the generation or control of SWDs has hitherto not been addressed, the spreading of discharges to different cortices was described [48].
Regulation (control) of SWDs in cerebellum
1) Confidence 0.16 Published 2008 Journal PLoS Biology Section Body Doc Link PMC2605917 Disease Relevance 0.21 Pain Relevance 0.45
Activation of basal ganglia circuits would allow endogenous regulation of SWDs, which can be artificially enhanced by neuromodulation techniques [49].
Regulation (regulation) of SWDs in basal ganglia
2) Confidence 0.16 Published 2008 Journal PLoS Biology Section Body Doc Link PMC2605917 Disease Relevance 0.25 Pain Relevance 0.28
In our data, the vmPFC and insular cortex lesion groups did not differ from controls in the SDs of point earnings on the task (Table 2).
Neg (not) Regulation (controls) of SDs in insular cortex
3) Confidence 0.12 Published 2008 Journal Brain Section Body Doc Link PMC2367692 Disease Relevance 0.20 Pain Relevance 0.03
We selected first S1BF because of recent evidence indicating its role as a cortical driver, second the ventrobasal thalamus because it is known that the thalamocortical loop is implicated in SWDs, and third the striatum because of various studies suggesting its role in the control of SWDs.
Regulation (control) of SWDs in thalamus associated with somatosensory cortex and thalamus
4) Confidence 0.11 Published 2008 Journal PLoS Biology Section Body Doc Link PMC2605917 Disease Relevance 0.07 Pain Relevance 0.16
After the age of 12 months and before 8 years, Stikkelbroeck et al. found no significant effect of glucocorticoid dose on height SDS [45].
Neg (no) Regulation (effect) of SDS
5) Confidence 0.02 Published 2010 Journal International Journal of Pediatric Endocrinology Section Body Doc Link PMC2817857 Disease Relevance 0.37 Pain Relevance 0

General Comments

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