INT231677

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Context Info
Confidence 0.18
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (CD47, THBS1) extracellular space (THBS1) extracellular region (THBS1)
structural molecule activity (THBS1) plasma membrane (CD47)
Anatomy Link Frequency
chondrocyte 1
CD47 (Homo sapiens)
THBS1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Mechanotransduction 26 90.84 High High
Osteoarthritis 10 5.00 Very Low Very Low Very Low
agonist 3 5.00 Very Low Very Low Very Low
metalloproteinase 2 5.00 Very Low Very Low Very Low
tetrodotoxin 1 5.00 Very Low Very Low Very Low
potassium channel 1 5.00 Very Low Very Low Very Low
Kinase C 1 5.00 Very Low Very Low Very Low
Immobilon 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Reprotox - General 1 2 43.04 Quite Low
Adhesions 4 9.08 Low Low
Osteoarthritis 24 5.00 Very Low Very Low Very Low
Carcinoma 3 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low
Disease 1 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 1 5.00 Very Low Very Low Very Low
Stress 1 5.00 Very Low Very Low Very Low
Skin Cancer 1 5.00 Very Low Very Low Very Low
Disease Progression 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Inhibition of the electrophysiological response of chondrocytes by anti-TSP-1 antibodies in addition to the function-blocking anti-CD47/IAP antibody Bric 126 suggests that TSP-CD47/IAP interactions may also be important in chondrocyte responses to mechanical stimulation.
CD47/IAP Binding (interactions) of TSP in chondrocyte
1) Confidence 0.18 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2374443 Disease Relevance 0 Pain Relevance 0.16

General Comments

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