INT231712

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.01
Pain Relevance 0.57

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL6) aging (IL6) extracellular region (IL6)
GAGE2C (Homo sapiens)
IL6 (Homo sapiens)
Pain Link Frequency Relevance Heat
Osteoarthritis 87 95.16 Very High Very High Very High
rheumatoid arthritis 1 74.00 Quite High
Pain 19 72.68 Quite High
Inflammation 6 66.16 Quite High
Lasting pain 1 39.76 Quite Low
cytokine 1 5.00 Very Low Very Low Very Low
Hyperalgesia 1 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoarthritis 87 95.16 Very High Very High Very High
Disease 10 76.48 Quite High
Rheumatoid Arthritis 1 74.00 Quite High
Pain 17 72.68 Quite High
INFLAMMATION 6 66.16 Quite High
Arthralgia 3 64.56 Quite High
Obesity 6 5.00 Very Low Very Low Very Low
Nicotine Addiction 4 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
Hyperalgesia 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The three promoter variations G-597A, G-572C and G-174C have been shown to influence IL-6 transcription through a complex interaction determined by the haplotype, and the G alleles at these loci have been found to associate with increased transcription of IL-6 [16].
G-572C Regulation (influence) of Transcription (transcription) of IL-6
1) Confidence 0.01 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2374458 Disease Relevance 1.01 Pain Relevance 0.57

General Comments

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