INT231737

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Context Info
Confidence 0.50
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 6
Disease Relevance 7.40
Pain Relevance 2.63

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
TFJ 2
chondrocytes 1
cartilage 1
lung 1
OAP (Homo sapiens)
Pain Link Frequency Relevance Heat
Osteoarthritis 305 100.00 Very High Very High Very High
cytokine 9 100.00 Very High Very High Very High
Pain 57 97.68 Very High Very High Very High
Inflammation 21 95.92 Very High Very High Very High
rheumatoid arthritis 5 84.04 Quite High
imagery 30 77.84 Quite High
Arthritis 4 50.24 Quite High
depression 1 39.72 Quite Low
ischemia 4 38.96 Quite Low
alcohol 7 17.80 Low Low
Disease Link Frequency Relevance Heat
Osteoarthritis 283 100.00 Very High Very High Very High
Frailty 31 100.00 Very High Very High Very High
Lung Injury 22 99.64 Very High Very High Very High
Disease 73 98.96 Very High Very High Very High
Injury 21 98.10 Very High Very High Very High
Adult Respiratory Distress Syndrome 43 97.92 Very High Very High Very High
Pain 57 97.68 Very High Very High Very High
INFLAMMATION 17 95.92 Very High Very High Very High
Necrosis 4 90.20 High High
Cancer 4 89.84 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The KL classification scheme is a validated method for classifying individual joints into one of five grades, with 0 representing healthy joints, 1 representing doubtful OA, 2 representing mild OA, 3 moderate OA, and 4 being the most severe radiographic disease.
Localization (representing) of doubtful OA in joints associated with disease and osteoarthritis
1) Confidence 0.50 Published 2010 Journal J: Section Body Doc Link PMC2909716 Disease Relevance 1.42 Pain Relevance 0.50
Finally, while this study focused on an unbiased analysis of the image content, a more comprehensive study can also include clinical data such as pain, history of injuries, relevant medication information, age, weight, BMI, and other clinical indicators that can be relevant to OA.
Localization (relevant) of OA associated with pain, injury and osteoarthritis
2) Confidence 0.50 Published 2010 Journal J: Section Body Doc Link PMC2909716 Disease Relevance 0.98 Pain Relevance 0.35
Importantly, the presence of baseline PFJ OA predicts structural deterioration in the TFJ compartment over 30 months (OR 2.31, 95% CI 1.37, 3.88) [7].
Localization (presence) of PFJ OA in TFJ associated with osteoarthritis
3) Confidence 0.39 Published 2008 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2556332 Disease Relevance 1.70 Pain Relevance 0.82
Although OA disease activity appears to be limited to involved joints, release of cytokines into the systemic circulation during the subclinical phase of OA may explain the association we have seen between hsCRP and tibial cartilage volume.
Localization (release) of OA in cartilage associated with disease, osteoarthritis and cytokine
4) Confidence 0.18 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2374464 Disease Relevance 1.72 Pain Relevance 0.62
Of perhaps greater significance, HTS enhanced the resolution of OA induced lung injury, as evidenced by a reduced severity of histologic injury, and reduced indices of inflammation, compared to control conditions.
Localization (resolution) of OA in lung associated with lung injury, inflammation and injury
5) Confidence 0.06 Published 2008 Journal BMC Pulm Med Section Body Doc Link PMC2467400 Disease Relevance 1.05 Pain Relevance 0.14
receptors appeared to be changed by nitric oxide and ROS levels and OA chondrocytes became insensitive to TGF?
Localization (chondrocytes) of OA in chondrocytes associated with osteoarthritis
6) Confidence 0.04 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2875624 Disease Relevance 0.53 Pain Relevance 0.20

General Comments

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