INT231748

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.95
Pain Relevance 0.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il6) extracellular region (Il6)
LOC690550 (Rattus norvegicus)
Il6 (Mus musculus)
Pain Link Frequency Relevance Heat
Arthritis 51 93.60 High High
Inflammatory mediators 2 89.12 High High
cytokine 15 84.64 Quite High
Inflammation 13 49.48 Quite Low
rheumatoid arthritis 24 41.76 Quite Low
Inflammatory response 1 34.56 Quite Low
antagonist 3 5.00 Very Low Very Low Very Low
methotrexate 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypersensitivity 3 97.36 Very High Very High Very High
Arthritis 54 93.60 High High
Disease 26 89.84 High High
INFLAMMATION 15 88.72 High High
Pressure And Volume Under Development 15 49.84 Quite Low
Rheumatoid Arthritis 24 41.76 Quite Low
Erythema 5 5.00 Very Low Very Low Very Low
Necrosis 2 5.00 Very Low Very Low Very Low
Cancer 2 5.00 Very Low Very Low Very Low
Sprains And Strains 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interestingly, both CP-690550 (78% reduction vs control) and the anti-TNF mAb (68% reduction vs control) significantly reduced serum IL-6 levels.
CP-690550 Negative_regulation (reduced) of IL-6
1) Confidence 0.01 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2374467 Disease Relevance 0.95 Pain Relevance 0.36

General Comments

This test has worked.

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