INT231751

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Context Info
Confidence 0.03
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.56
Pain Relevance 0.67

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeleton (Jak3) intracellular (Jak3) kinase activity (Jak3)
cytoplasm (Jak3)
Il2rg (Mus musculus)
Jak3 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 30 98.64 Very High Very High Very High
methotrexate 4 80.32 Quite High
rheumatoid arthritis 48 74.32 Quite High
Arthritis 102 67.04 Quite High
antagonist 6 57.68 Quite High
Inflammation 26 46.40 Quite Low
Inflammatory mediators 4 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypersensitivity 6 95.88 Very High Very High Very High
Adverse Drug Reaction 2 86.88 High High
Rheumatoid Arthritis 48 74.32 Quite High
Disease 52 70.56 Quite High
Arthritis 108 67.04 Quite High
Necrosis 4 56.68 Quite High
Cancer 4 56.32 Quite High
INFLAMMATION 30 46.40 Quite Low
Synovitis 2 22.96 Low Low
Pressure And Volume Under Development 30 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CP-690550 is a small molecule inhibitor of the tyrosine kinase Janus kinase 3 (JAK3), an enzyme that is associated with the common gamma chain (?
common gamma chain Binding (associated) of JAK3
1) Confidence 0.03 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2374467 Disease Relevance 0.78 Pain Relevance 0.33
CP-690550 is a small molecule inhibitor of the tyrosine kinase Janus kinase 3 (JAK3), an enzyme that is associated with the common gamma chain (?
common gamma chain Binding (associated) of Janus kinase 3
2) Confidence 0.02 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2374467 Disease Relevance 0.78 Pain Relevance 0.33

General Comments

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