INT231758

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Context Info
Confidence 0.08
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.23
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (IRF6, HMOX1) nucleus (IRF6, HMOX1) small molecule metabolic process (HMOX1)
endoplasmic reticulum (HMOX1) enzyme binding (HMOX1) DNA binding (IRF6)
Anatomy Link Frequency
monocytes 2
IRF6 (Homo sapiens)
HMOX1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Infliximab 2 99.30 Very High Very High Very High
Inflammatory response 7 28.00 Quite Low
Inflammation 16 5.00 Very Low Very Low Very Low
rheumatoid arthritis 10 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
methotrexate 1 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 79 90.60 High High
INFLAMMATION 24 27.64 Quite Low
Rheumatic Diseases 4 18.80 Low Low
Hemophagocytic Lymphohistiocytosis 1 7.36 Low Low
Rheumatoid Arthritis 10 5.00 Very Low Very Low Very Low
Shock 4 5.00 Very Low Very Low Very Low
Ulcers 2 5.00 Very Low Very Low Very Low
Uveitis 2 5.00 Very Low Very Low Very Low
Necrosis 2 5.00 Very Low Very Low Very Low
Autoimmune Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
antibody infliximab did not eliminate the suppressive effect of LPS on HO-1 expression in monocytes in vitro (Additional file 3).
LPS Regulation (effect) of Gene_expression (expression) of HO-1 in monocytes associated with infliximab
1) Confidence 0.08 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2374472 Disease Relevance 0.23 Pain Relevance 0.05

General Comments

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