INT231772

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Context Info
Confidence 0.21
First Reported 2008
Last Reported 2008
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.96
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (TNF, HMOX1) signal transduction (TNF, HMOX1) transmembrane transport (HMOX1)
oxidoreductase activity (HMOX1) cell death (HMOX1) plasma membrane (TNF)
TNF (Homo sapiens)
HMOX1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammatory response 7 78.96 Quite High
Inflammation 16 59.44 Quite High
ischemia 1 41.44 Quite Low
rheumatoid arthritis 10 5.00 Very Low Very Low Very Low
Infliximab 2 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
methotrexate 1 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 79 97.64 Very High Very High Very High
INFLAMMATION 24 78.56 Quite High
Lung Injury 2 51.68 Quite High
Reperfusion Injury 1 42.20 Quite Low
Cv Unclassified Under Development 1 41.44 Quite Low
Rheumatic Diseases 4 35.04 Quite Low
Autoimmune Disease 2 13.32 Low Low
Rheumatoid Arthritis 10 5.00 Very Low Very Low Very Low
Shock 4 5.00 Very Low Very Low Very Low
Ulcers 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, TNF may also contribute to defective HO-1 expression in vivo, because other types of cells also produce TNF in BD.
TNF Spec (may) Positive_regulation (contribute) of Gene_expression (expression) of HO-1 associated with disease
1) Confidence 0.21 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2374472 Disease Relevance 0.96 Pain Relevance 0.10

General Comments

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