INT231797

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Context Info
Confidence 0.02
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.49
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Glrb, TNF) signal transduction (TNF) extracellular space (TNF)
transport (Glrb) extracellular region (TNF) endoplasmic reticulum (Glrb)
Glrb (Mus musculus)
TNF (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 10 100.00 Very High Very High Very High
Inflammation 16 90.32 High High
Infliximab 24 84.72 Quite High
corticosteroid 1 69.72 Quite High
Arthritis 4 44.88 Quite Low
methotrexate 3 35.80 Quite Low
Etanercept 6 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
Adalimumab 3 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 10 100.00 Very High Very High Very High
Crohn's Disease 6 99.80 Very High Very High Very High
Disease 22 99.16 Very High Very High Very High
Systemic Lupus Erythematosus 55 98.90 Very High Very High Very High
INFLAMMATION 18 90.32 High High
Proteinuria 4 83.28 Quite High
Nephritis 7 68.64 Quite High
Renal Disease 16 68.20 Quite High
Necrosis 16 50.00 Quite Low
Cancer 16 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Whereas drug-induced lupus-like disease is an uncommon, but established, adverse effect of TNF blockade in patients with RA, SpA, or CD, these autoantibodies hitherto have not induced lupus flares.
SpA Regulation (effect) of Negative_regulation (blockade) of TNF associated with crohn's disease, rheumatoid arthritis, disease and systemic lupus erythematosus
1) Confidence 0.02 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2374473 Disease Relevance 1.49 Pain Relevance 0.25

General Comments

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