INT231844

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Context Info
Confidence 0.00
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.63
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Pcdh8, Akt1) transport (Akt1) aging (Akt1)
enzyme binding (Akt1) carbohydrate metabolic process (Akt1) cytoplasm (Akt1)
Pcdh8 (Mus musculus)
Akt1 (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 4 75.24 Quite High
Inflammation 38 61.00 Quite High
cytokine 4 56.32 Quite High
Inflammatory mediators 1 51.76 Quite High
Inflammatory response 1 23.16 Low Low
corticosteroid 1 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
cva 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Lung Injury 40 97.16 Very High Very High Very High
Adult Respiratory Distress Syndrome 21 67.20 Quite High
Pneumonia 9 61.00 Quite High
Syndrome 4 58.92 Quite High
INFLAMMATION 31 57.36 Quite High
Necrosis 1 53.52 Quite High
Cancer 1 53.16 Quite High
Sprains And Strains 2 49.28 Quite Low
Pressure And Volume Under Development 1 19.36 Low Low
Stress 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Using an in vitro model of VILI, we demonstrated the protective effects of OxPAPC on barrier disruption induced by high-magnitude (18%) CS and thrombin and linked them with OxPAPC-induced reduction in Rho activity and modest increases in Rac activity.
OxPAPC-induced Negative_regulation (reduction) of Positive_regulation (increases) of Rac associated with lung injury
1) Confidence 0.00 Published 2008 Journal Crit Care Section Body Doc Link PMC2374596 Disease Relevance 0.63 Pain Relevance 0.15

General Comments

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