INT231865

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.05
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (ARHGDIA, Sergef) cytosol (ARHGDIA) nucleolus (Sergef)
nucleus (Sergef) cytoskeleton (ARHGDIA)
ARHGDIA (Homo sapiens)
Sergef (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 4 73.12 Quite High
Inflammation 38 50.00 Quite Low
cytokine 4 12.60 Low Low
corticosteroid 1 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
cva 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 9 54.88 Quite High
INFLAMMATION 31 50.00 Quite Low
Adult Respiratory Distress Syndrome 21 49.84 Quite Low
Lung Injury 40 16.68 Low Low
Pneumonia 9 5.00 Very Low Very Low Very Low
Syndrome 4 5.00 Very Low Very Low Very Low
Sprains And Strains 2 5.00 Very Low Very Low Very Low
Thrombosis 1 5.00 Very Low Very Low Very Low
Exsanguination 1 5.00 Very Low Very Low Very Low
Necrosis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Recent studies suggest downregulation of the Rho pathway by Rac-mediated signaling cascades [60] via (a) direct Rac interaction with RhoGDI [59], (b) PAK1-dependent inhibition of Rho-specific GEF p115RhoGEF, and (c) stimulation of Rho-specific GTPase-activating protein p190-RhoGAP by Rac [61].
RhoGDI Negative_regulation (inhibition) of GEF
1) Confidence 0.01 Published 2008 Journal Crit Care Section Body Doc Link PMC2374596 Disease Relevance 0.05 Pain Relevance 0.04

General Comments

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