INT231978

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Context Info
Confidence 0.36
First Reported 2008
Last Reported 2011
Negated 0
Speculated 1
Reported most in Body
Documents 9
Total Number 10
Disease Relevance 8.33
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (SERPINB3) cytoplasm (SERPINB3)
Anatomy Link Frequency
bladder 1
SERPINB3 (Homo sapiens)
Pain Link Frequency Relevance Heat
alcohol 6 29.72 Quite Low
Pain 9 5.00 Very Low Very Low Very Low
pruritus 7 5.00 Very Low Very Low Very Low
medulla 5 5.00 Very Low Very Low Very Low
diclofenac 4 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
lidocaine 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Basal And Squamous Cell Skin Cancer 142 100.00 Very High Very High Very High
Skin Cancer 128 100.00 Very High Very High Very High
Cancer 239 99.92 Very High Very High Very High
Papillomavirus Infection 112 99.44 Very High Very High Very High
Nicotine Addiction 88 99.32 Very High Very High Very High
Malignant Neoplastic Disease 14 99.18 Very High Very High Very High
Carcinoma 10 99.12 Very High Very High Very High
Lichen Sclerosus Et Atrophicus 64 98.68 Very High Very High Very High
Adenocarcinoma 34 97.32 Very High Very High Very High
Bladder Cancer 35 94.32 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To be included in the study, a patient had to meet the following criteria: 1) be diagnosed with T3b, T4a, or T4b transitional carcinoma of the bladder at our institution from January 2001 to August 2008, 2) have undergone transurethral resection of the bladder tumor and be followed up for at least 12 months, 3) complete each chemotherapy session, 4) patients with one of the above-mentioned stages but for whom surgery was not an option because of accompanying medical illnesses, 5) patients having problems of postoperative male sexual dysfunction and urinary incontinence or discomfort with urinary diversion, 6) patients of an old age, and 7) patients who rejected radical cystectomy as a treatment plan.
T4a Binding (diagnosed) of in bladder associated with reprotox - general 3, bladder cancer, overactive bladder and carcinoma
1) Confidence 0.36 Published 2010 Journal Korean Journal of Urology Section Body Doc Link PMC2924555 Disease Relevance 0.81 Pain Relevance 0
The results showed that smoking habit and age were independently associated with SCC.
SCC Binding (associated) of associated with nicotine addiction and skin cancer
2) Confidence 0.15 Published 2010 Journal BMC Public Health Section Body Doc Link PMC2864212 Disease Relevance 1.01 Pain Relevance 0
The study has also found that SCC was more common in older patients, that is, confirming the association with older patients and the higher incidence of SCC.
SCC Binding (association) of associated with skin cancer
3) Confidence 0.12 Published 2010 Journal BMC Public Health Section Body Doc Link PMC2864212 Disease Relevance 1.00 Pain Relevance 0
We have previously demonstrated that 2 of 6 LS lesions exhibited monoclonality, implying that certain important molecular alterations might occur in some LS lesions well before histologically apparent malignant transformation to differentiated VIN or keratinizing SCC occurs [35].
SCC Spec (might) Binding (keratinizing) of associated with malignant neoplastic disease, basal and squamous cell skin cancer, cancer and lichen sclerosus et atrophicus
4) Confidence 0.03 Published 2011 Journal Journal of Skin Cancer Section Body Doc Link PMC3003991 Disease Relevance 2.43 Pain Relevance 0
Keratinizing SCC develops within a background of lichen sclerosus (LS) through a differentiated VIN.
SCC Binding (Keratinizing) of associated with cancer, basal and squamous cell skin cancer and lichen sclerosus et atrophicus
5) Confidence 0.03 Published 2011 Journal Journal of Skin Cancer Section Abstract Doc Link PMC3003991 Disease Relevance 2.07 Pain Relevance 0
The ewe's milk presented with a SCC as high as others but the length of lactation was shorter compared to most of the other ewes, although ewe number 140/6 also had a short lactation but fed a lamb that accumulated PrPd in RAMALT.
SCC Binding (presented) of
6) Confidence 0.03 Published 2008 Journal BMC Vet Res Section Body Doc Link PMC2374774 Disease Relevance 0.20 Pain Relevance 0
g/ml for SCC9, and 93.1, 132.8 and 93.3 ?
SCC9 Binding (132.8) of
7) Confidence 0.02 Published 2008 Journal Mar Drugs Section Body Doc Link PMC2630851 Disease Relevance 0.21 Pain Relevance 0
g/ml for SCC9, and 38.7, 48.9 and 49.1 ?
SCC9 Binding (48.9) of
8) Confidence 0.02 Published 2008 Journal Mar Drugs Section Body Doc Link PMC2630851 Disease Relevance 0.19 Pain Relevance 0
g/ml for SCC9, and 93.1, 132.8 and 93.3 ?
SCC9 Binding (93.3) of
9) Confidence 0.02 Published 2008 Journal Mar Drugs Section Body Doc Link PMC2630851 Disease Relevance 0.21 Pain Relevance 0
g/ml for SCC9, and 38.7, 48.9 and 49.1 ?
SCC9 Binding (49.1) of
10) Confidence 0.02 Published 2008 Journal Mar Drugs Section Body Doc Link PMC2630851 Disease Relevance 0.19 Pain Relevance 0

General Comments

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