INT232012

Context Info Confidence 0.18 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.72 Pain Relevance 0.04

extracellular region (SERPING1, C1R) peptidase activity (C1R) extracellular space (SERPING1)

SERPING1 (Homo sapiens) C1R (Homo sapiens)

Pain Link Frequency Relevance Heat Inflammation 2 84.60 bradykinin 20 40.16 Pain score 1 36.96 Pain 5 26.32 antagonist 5 5.00 vincristine 1 5.00

Disease Link Frequency Relevance Heat Hereditary Angioedema 64 99.36 INFLAMMATION 2 84.60 Injury 2 83.92 Infection 1 83.60 Laryngeal Edema 2 67.00 Pressure And Volume Under Development 31 54.08 Emergencies 1 45.64 Unconsciousness 1 42.04 Shock 1 41.00 Diarrhoea 2 39.96

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

C1-inhibitor inactivates C1r and C1s, the serine protease subcomponents of the first component of the complement pathway [20].

C1-inhibitor Negative_regulation (inactivates) of C1r

1) Confidence 0.18 Published 2008 Journal Clin Mol Allergy Section Body Doc Link PMC2374835 Disease Relevance 0.72 Pain Relevance 0.04

General Comments

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