INT232065

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Context Info
Confidence 0.04
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.81
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (DDR1) cell adhesion (DDR1) plasma membrane (DDR1)
Anatomy Link Frequency
nucleus 1
DDR1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Potency 1 30.16 Quite Low
cytokine 8 5.00 Very Low Very Low Very Low
imagery 3 5.00 Very Low Very Low Very Low
withdrawal 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
cva 2 5.00 Very Low Very Low Very Low
Bile 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Influenza Virus Infection 56 99.50 Very High Very High Very High
Genomic Instability 2 78.88 Quite High
Influenza In Birds 36 71.92 Quite High
Malignant Neoplastic Disease 1 70.36 Quite High
Apoptosis 1 68.72 Quite High
Cancer 19 45.04 Quite Low
Renal Cancer 43 23.84 Low Low
Von Hippel-lindau Syndrome 9 15.44 Low Low
Infection 37 5.00 Very Low Very Low Very Low
Toxicity 18 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Ligand binding results in RTK dimerization that activates kinase function and the ensuing cascade, subject to complex regulatory controls.
RTK Binding (binding) of
1) Confidence 0.04 Published 2008 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2727778 Disease Relevance 0.22 Pain Relevance 0
Although a direct interaction between NEP and NP proteins has not been shown, the severely defective growth of reassortants possessing heterologous M and NS relative to NP suggests an unidentified crosstalk between these viral proteins, with the possible involvement of a host protein(s).
NEP Binding (interaction) of
2) Confidence 0.04 Published 2008 Journal PLoS Pathogens Section Body Doc Link PMC2374906 Disease Relevance 0.28 Pain Relevance 0
In the nucleus, the influenza nuclear export protein (NEP; encoded by the NS gene) interacts with the M1 protein, which binds to the newly assembled viral RNP.
NEP Binding (interacts) of in nucleus associated with influenza virus infection
3) Confidence 0.03 Published 2008 Journal PLoS Pathogens Section Body Doc Link PMC2374906 Disease Relevance 0.32 Pain Relevance 0

General Comments

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