INT232066

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Context Info
Confidence 0.13
First Reported 2007
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 7
Disease Relevance 0.28
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (PNP) small molecule metabolic process (PNP) cytoskeleton (PNP)
intracellular (PNP) cytoplasm (PNP)
PNP (Homo sapiens)
Pain Link Frequency Relevance Heat
anesthesia 7 11.08 Low Low
adenocard 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Influenza Virus Infection 56 89.20 High High
Influenza In Birds 36 62.12 Quite High
Cytomegalovirus Infection 5 33.60 Quite Low
Infection 36 5.00 Very Low Very Low Very Low
Age-related Macular Degeneration 25 5.00 Very Low Very Low Very Low
Disorders Of Creatine Metabolism 10 5.00 Very Low Very Low Very Low
Stress 10 5.00 Very Low Very Low Very Low
Weight Loss 8 5.00 Very Low Very Low Very Low
Lung Cancer 6 5.00 Very Low Very Low Very Low
Uveitis 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
On the other hand, highly crosslinked pSOD-HSA NP with a size of about 120 nm, showed continuous release profile, with substantially lower initial burst.
NP Binding (crosslinked) of
1) Confidence 0.13 Published 2007 Journal Molecular Vision Section Body Doc Link PMC2768759 Disease Relevance 0 Pain Relevance 0
As shown in Figure 2C in vitro pSOD release from HSA NP with low crosslinking and a particle size of about 160 nm, is a biphasic curve including a fast-release phase, during which 65% of the drug load was released in the first 6 h, and a slow but steady release phase, accounting for the release of the remaining plasmid load in the next 44 h.
NP Binding (crosslinking) of
2) Confidence 0.13 Published 2007 Journal Molecular Vision Section Body Doc Link PMC2768759 Disease Relevance 0 Pain Relevance 0
Subsequent studies were primarily conducted with high crosslinking HSA NP, unless otherwise stated.


NP Binding (crosslinking) of
3) Confidence 0.13 Published 2007 Journal Molecular Vision Section Body Doc Link PMC2768759 Disease Relevance 0 Pain Relevance 0
Transmission electron microscopic image of HSA NP was acquired with an electron microscope (Philips-410LS, FEI Co., Hillsboro, OR) after the nanoparticles were negatively stained with Vanadium (NanoVanĀ®, Nanoprobes, Inc., Yaphank, NY).
NP Binding (image) of
4) Confidence 0.10 Published 2007 Journal Molecular Vision Section Body Doc Link PMC2768759 Disease Relevance 0 Pain Relevance 0
Second, 0.1 instead of the reported 0.002 mg glutaraldehyde/mg HSA [29], the NP crosslinking reagent, was used.
NP Binding (crosslinking) of
5) Confidence 0.09 Published 2007 Journal Molecular Vision Section Body Doc Link PMC2768759 Disease Relevance 0 Pain Relevance 0
Although a direct interaction between NEP and NP proteins has not been shown, the severely defective growth of reassortants possessing heterologous M and NS relative to NP suggests an unidentified crosstalk between these viral proteins, with the possible involvement of a host protein(s).
NP Binding (interaction) of
6) Confidence 0.06 Published 2008 Journal PLoS Pathogens Section Body Doc Link PMC2374906 Disease Relevance 0.28 Pain Relevance 0
Notably, the severely impaired rH5N1 viruses in group 4 (Figure 2) were all characterized by the association of the nucleoprotein (NP) gene from WY03 virus with matrix (M) and/or nonstructural (NS) genes derived from TH04 virus.
NP Binding (association) of
7) Confidence 0.05 Published 2008 Journal PLoS Pathogens Section Body Doc Link PMC2374906 Disease Relevance 0 Pain Relevance 0

General Comments

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