INT232236

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Context Info
Confidence 0.35
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.36
Pain Relevance 0.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

oxidoreductase activity (Hmgcr) embryo development (Hmgcr)
Anatomy Link Frequency
plasma 2
pupil 2
Hmgcr (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 142 96.80 Very High Very High Very High
imagery 3 91.28 High High
Inflammatory response 25 35.52 Quite Low
chemokine 8 22.24 Low Low
cytokine 5 5.00 Very Low Very Low Very Low
Inflammatory mediators 5 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
aspirin 2 5.00 Very Low Very Low Very Low
addiction 2 5.00 Very Low Very Low Very Low
COX2 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 37 98.48 Very High Very High Very High
Stress 111 96.80 Very High Very High Very High
Atherosclerosis 37 92.84 High High
INFLAMMATION 112 90.76 High High
Cirrhosis 6 78.84 Quite High
Targeted Disruption 68 51.44 Quite High
Urological Neuroanatomy 6 27.56 Quite Low
Necrosis 3 18.44 Low Low
Cancer 3 18.08 Low Low
Hyperlipidemia 4 16.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For example, the expression of genes involved in endogenous cholesterol synthesis (for example, HMG-CoA reductase) and cholesterol uptake from plasma (for example, LDLR) is diminished.
Negative_regulation (diminished) of Gene_expression (expression) of HMG-CoA reductase in plasma
1) Confidence 0.35 Published 2007 Journal Genome Biol Section Body Doc Link PMC2375038 Disease Relevance 1.31 Pain Relevance 0.23
This suggests that under these conditions red cones define the magnitude of pupil constriction in the range of ?
Negative_regulation (define) of Gene_expression (cones) of red in pupil
2) Confidence 0.08 Published 2010 Journal Neuron Section Body Doc Link PMC2875410 Disease Relevance 0.05 Pain Relevance 0
AP activity was visualized in red using Vector Red (Vector Labs).
Negative_regulation (visualized) of Gene_expression (using) of Red
3) Confidence 0.03 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2954806 Disease Relevance 0 Pain Relevance 0.08

General Comments

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