INT23228

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Context Info
Confidence 0.23
First Reported 1990
Last Reported 2008
Negated 1
Speculated 2
Reported most in Body
Documents 2
Total Number 4
Disease Relevance 0.48
Pain Relevance 0.57

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (OXT) extracellular space (OXT) extracellular region (OXT)
response to stress (OXT) cytoplasm (OXT)
OXT (Homo sapiens)
Pain Link Frequency Relevance Heat
Endogenous opioid 4 100.00 Very High Very High Very High
narcan 12 92.68 High High
Central nervous system 8 83.72 Quite High
Neuropeptide 36 52.32 Quite High
agonist 8 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
Intracerebroventricular 4 5.00 Very Low Very Low Very Low
isoflurane 4 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
Rostral ventrolateral medulla 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Premature Birth 4 92.00 High High
Nicotine Addiction 2 81.68 Quite High
Pressure Volume 2 Under Development 4 79.84 Quite High
Pre-term Labor 4 76.08 Quite High
Stress 2 10.32 Low Low
Depression 2 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 2 5.00 Very Low Very Low Very Low
Natriuresis 2 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 2 5.00 Very Low Very Low Very Low
Heart Rate Under Development 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We conclude that endogenous opioid peptides do not modulate OT release during breast feeding or breast stimulation in women.
Neg (not) Regulation (modulate) of Localization (release) of OT associated with endogenous opioid
1) Confidence 0.23 Published 1990 Journal Clin. Endocrinol. (Oxf) Section Abstract Doc Link 2401100 Disease Relevance 0 Pain Relevance 0.29
We have investigated the role of endogenous opioid peptides in the release of oxytocin (OT) in response to breast feeding and breast stimulation in humans.
Spec (investigated) Regulation (role) of Localization (release) of oxytocin associated with endogenous opioid
2) Confidence 0.23 Published 1990 Journal Clin. Endocrinol. (Oxf) Section Abstract Doc Link 2401100 Disease Relevance 0 Pain Relevance 0.21
Previous studies in adult animals showed that hyperosmolality is a potent stimulus in the control of AVP and OT secretion [41-43].
Regulation (control) of Localization (secretion) of OT
3) Confidence 0.10 Published 2008 Journal BMC Dev Biol Section Body Doc Link PMC2570685 Disease Relevance 0.32 Pain Relevance 0.04
However, the results of pronounced pressor responses in the present as well as previous study [15] after the i.c.v. carbachol do not support the possibility that volume mechanisms may contribute to AVP and OT release by central cholinergic stimulation in utero.
Spec (may) Regulation (contribute) of Localization (release) of OT
4) Confidence 0.10 Published 2008 Journal BMC Dev Biol Section Body Doc Link PMC2570685 Disease Relevance 0.16 Pain Relevance 0.03

General Comments

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