INT23239

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Context Info
Confidence 0.10
First Reported 1986
Last Reported 1990
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.27
Pain Relevance 0.54

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Got1) biosynthetic process (Got1) cellular amino acid metabolic process (Got1)
lysosome (Got1) cytoplasm (Got1)
Got1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Paracetamol 3 97.00 Very High Very High Very High
Opioid 2 96.96 Very High Very High Very High
addiction 2 96.68 Very High Very High Very High
Pain 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Opiate Addiction 2 96.96 Very High Very High Very High
Injury 1 95.76 Very High Very High Very High
Hepatotoxicity 1 75.00 Quite High
Congenital Anomalies 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
All subjects with significant elevations of transaminase values in these studies took daily naltrexone dosages higher than recommended for opioid addiction.
Positive_regulation (elevations) of Regulation (values) of transaminase associated with addiction and opioid
1) Confidence 0.10 Published 1986 Journal NIDA Res. Monogr. Section Abstract Doc Link 3092099 Disease Relevance 0.10 Pain Relevance 0.28
All had markedly elevated serum transaminase values (aspartate aminotransferase greater than 4000 U/L) and prolonged prothrombin times.
Positive_regulation (elevated) of Regulation (values) of transaminase
2) Confidence 0.03 Published 1990 Journal South. Med. J. Section Abstract Doc Link 2402650 Disease Relevance 0.17 Pain Relevance 0.26

General Comments

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