INT232395

Context Info Confidence 0.05 First Reported 2007 Last Reported 2007 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0

LYPLA2P1 (Homo sapiens)

Pain Link Frequency Relevance Heat withdrawal 3 5.00 tolerance 2 5.00 Piles 1 5.00 Arthritis 1 5.00 headache 1 5.00 Bioavailability 1 5.00

Disease Link Frequency Relevance Heat Leishmaniasis 31 50.00 Apoptosis 5 41.52 Death 1 34.92 Cancer 2 22.88 Meningoencephalitis 1 16.92 American Trypanosomiasis 1 13.80 Retinal Diseases 1 12.08 Vomiting 20 5.00 Diarrhoea 16 5.00 Toxicity 8 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

For transport across the membrane, a putative transporter was recently identified; a Leishmania P-type ATPase gene, belonging to the aminophospholipid translocase (APT) subfamily termed LdMT (L. donovani Miltefosine Transporter) has been cloned.

Localization (translocase) of APT

1) Confidence 0.05 Published 2007 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2376078 Disease Relevance 0 Pain Relevance 0

General Comments

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