INT232559

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Context Info
Confidence 0.19
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.26
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Map3k1, Esr1) enzyme binding (Esr1) DNA binding (Esr1)
protein complex (Esr1) lipid binding (Esr1) cytoskeleton (Map3k1)
Map3k1 (Mus musculus)
Esr1 (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 4 99.16 Very High Very High Very High
Pain 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 1 93.28 High High
Breast Cancer 24 88.32 High High
Advanced Or Metastatic Breast Cancer 4 77.04 Quite High
Disease Progression 2 34.16 Quite Low
Death 3 27.16 Quite Low
Recurrence 9 26.88 Quite Low
Cancer 13 5.00 Very Low Very Low Very Low
Noninfiltrating Intraductal Carcinoma 5 5.00 Very Low Very Low Very Low
Ductal Carcinoma 3 5.00 Very Low Very Low Very Low
Metastasis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Another feature of interest is that MEKK1, a downstream Her-2 signalling mediator activates ER and potentiates the agonist effect of tamoxifen [41].
MEKK1 Positive_regulation (activates) of ER associated with agonist
1) Confidence 0.19 Published 2008 Journal Int Semin Surg Oncol Section Body Doc Link PMC2383915 Disease Relevance 0.26 Pain Relevance 0.09

General Comments

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