INT232603

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Context Info
Confidence 0.50
First Reported 2008
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.23
Pain Relevance 1.34

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Gria1) transport (Gria1) endoplasmic reticulum (Gria1)
plasma membrane (Gria1) protein complex (Gria1)
Gria1 (Mus musculus)
Pain Link Frequency Relevance Heat
Glutamate receptor 41 100.00 Very High Very High Very High
Anterior cingulate cortex 82 99.60 Very High Very High Very High
long-term potentiation 57 99.12 Very High Very High Very High
depression 58 87.60 High High
nMDA receptor 26 84.32 Quite High
Hippocampus 4 80.72 Quite High
Thalamus 2 28.40 Quite Low
Calcium channel 1 26.24 Quite Low
Glutamate 6 20.84 Low Low
Lasting pain 14 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Depression 58 87.60 High High
Pain 24 5.00 Very Low Very Low Very Low
Hypersensitivity 9 5.00 Very Low Very Low Very Low
INFLAMMATION 8 5.00 Very Low Very Low Very Low
Nociception 7 5.00 Very Low Very Low Very Low
Targeted Disruption 6 5.00 Very Low Very Low Very Low
Injury 5 5.00 Very Low Very Low Very Low
Inflammatory Pain 5 5.00 Very Low Very Low Very Low
Sprains And Strains 4 5.00 Very Low Very Low Very Low
Congenital Anomalies 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thus, in the ACC of adult mice, the interaction between the C terminus of GluA1 and PDZ domain proteins is required for the induction of LTP.
Positive_regulation (required) of GluA1 Binding (interaction) of associated with long-term potentiation and anterior cingulate cortex
1) Confidence 0.50 Published 2009 Journal Mol Pain Section Body Doc Link PMC2734546 Disease Relevance 0 Pain Relevance 0.66
Furthermore, inducible ablation of GluR?
Positive_regulation (inducible) of GluR Binding (ablation) of associated with glutamate receptor
2) Confidence 0.28 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2386150 Disease Relevance 0.23 Pain Relevance 0.68

General Comments

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