INT232633

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Context Info
Confidence 0.27
First Reported 2008
Last Reported 2009
Negated 3
Speculated 1
Reported most in Body
Documents 2
Total Number 4
Disease Relevance 2.60
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Opa1) mitochondrion organization (Opa1) GTPase activity (Opa1)
Anatomy Link Frequency
fibroblasts 2
Opa1 (Mus musculus)
Pain Link Frequency Relevance Heat
Pain 26 5.00 Very Low Very Low Very Low
depression 18 5.00 Very Low Very Low Very Low
pruritus 18 5.00 Very Low Very Low Very Low
Inflammation 10 5.00 Very Low Very Low Very Low
headache 8 5.00 Very Low Very Low Very Low
cva 4 5.00 Very Low Very Low Very Low
Dysuria 4 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
abdominal pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Systemic Mastocytosis 78 97.64 Very High Very High Very High
Optic Disorders 16 94.48 High High
Apoptosis 8 91.44 High High
Mastocytosis 178 90.88 High High
Pallor 4 77.20 Quite High
Scotoma 8 74.40 Quite High
Disease 54 71.24 Quite High
Cutaneous Mastocytosis 48 69.04 Quite High
Ganglion Cysts 6 62.32 Quite High
Optic Atrophy 12 59.28 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In spite of the mutation, there was no quantitative modification of OPA1 expression in the patientÂ’s fibroblasts.
Neg (no) Regulation (modification) of Gene_expression (expression) of OPA1 in fibroblasts
1) Confidence 0.27 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2661005 Disease Relevance 0.51 Pain Relevance 0
We also observed no alteration of the OPA1 expression pattern in these cells (Figure 7).


Neg (no) Regulation (alteration) of Gene_expression (expression) of OPA1
2) Confidence 0.27 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2661005 Disease Relevance 0.54 Pain Relevance 0
As shown in Table 1, there was no significant difference between the OPA score according to the presence of an elevated (?
Neg (no) Regulation (difference) of Gene_expression (score) of OPA
3) Confidence 0.05 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2386235 Disease Relevance 0.70 Pain Relevance 0
We also examined the correlation between the OPA score and the total serum tryptase level because a level ?
Spec (examined) Regulation (correlation) of Gene_expression (score) of OPA
4) Confidence 0.05 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2386235 Disease Relevance 0.85 Pain Relevance 0

General Comments

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