INT232634

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Context Info
Confidence 0.75
First Reported 2008
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.11
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Opa1) mitochondrion organization (Opa1) GTPase activity (Opa1)
Opa1 (Mus musculus)
Pain Link Frequency Relevance Heat
Pain 13 5.00 Very Low Very Low Very Low
depression 9 5.00 Very Low Very Low Very Low
pruritus 9 5.00 Very Low Very Low Very Low
Inflammation 5 5.00 Very Low Very Low Very Low
headache 4 5.00 Very Low Very Low Very Low
cva 2 5.00 Very Low Very Low Very Low
Dysuria 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Mastocytosis 89 98.56 Very High Very High Very High
Atrophy 7 84.60 Quite High
Ganglion Cysts 3 83.00 Quite High
Optic Disorders 8 76.12 Quite High
Apoptosis 4 75.28 Quite High
Scotoma 4 70.24 Quite High
Pallor 2 68.28 Quite High
Autosomal Dominant Optic Atrophy 2 61.56 Quite High
Optic Atrophy 6 58.64 Quite High
Disease 27 56.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The OPA1 protein is localized to the mitochondrial intermembrane space, where it facilitates fusion between mitochondria [11].
Localization (localized) of OPA1
1) Confidence 0.75 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2661005 Disease Relevance 0.63 Pain Relevance 0
In 2004, 363 mastocytosis patients and 90 controls in France were asked to rate to their overall disability (OPA score) and the severity of 38 individual symptoms.
Localization (disability) of OPA associated with mastocytosis
2) Confidence 0.08 Published 2008 Journal PLoS ONE Section Abstract Doc Link PMC2386235 Disease Relevance 0.47 Pain Relevance 0

General Comments

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