INT232636

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Context Info
Confidence 0.39
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 1.98
Pain Relevance 0.98

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

pigmentation (Kit) cell differentiation (Kit) extracellular space (Kit)
plasma membrane (Kit) nucleus (Kit) kinase activity (Kit)
Anatomy Link Frequency
hemopoietic progenitor cells 2
Mast cells 2
Kit (Mus musculus)
Pain Link Frequency Relevance Heat
spastic colon 93 99.68 Very High Very High Very High
Arthritis 15 84.08 Quite High
Inflammatory marker 1 83.84 Quite High
Pain 29 72.56 Quite High
depression 19 71.36 Quite High
Inflammation 27 70.32 Quite High
Pain score 12 67.04 Quite High
substance P 15 52.76 Quite High
qutenza 4 50.00 Quite Low
pruritus 9 25.32 Quite Low
Disease Link Frequency Relevance Heat
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super

95 99.68 Very High Very High Very High
Cancer 72 84.52 Quite High
Arthritis 8 84.08 Quite High
INFLAMMATION 26 83.52 Quite High
Triploidy 2 74.88 Quite High
Pain 37 72.56 Quite High
Depression 21 71.36 Quite High
Anxiety Disorder 8 70.16 Quite High
Multiple Sclerosis 12 66.68 Quite High
Systemic Lupus Erythematosus 21 66.36 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
PCR products were purified with the Geneclean III kit (Qbiogene) and directly sequenced using a BigDye terminator kit v1.1 (Applied Biosystems) with primers 5?
Positive_regulation (sequenced) of kit Binding (using) of
1) Confidence 0.39 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2386235 Disease Relevance 0 Pain Relevance 0
EGFr, c-Kit, and CD74 staining also showed an increased mean fluorescence intensity, whereas IL-13R?
Positive_regulation (increased) of c-Kit Binding (intensity) of
2) Confidence 0.16 Published 2010 Journal Head Neck Oncol Section Body Doc Link PMC2841166 Disease Relevance 0.42 Pain Relevance 0
C-kit is a proto-oncogene encoding a tyrosine kinase that (together with its ligand) is important for the maintenance of hemopoietic progenitor cells [19].
Positive_regulation (important) of C-kit Binding (ligand) of in hemopoietic progenitor cells
3) Confidence 0.13 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2592775 Disease Relevance 0.61 Pain Relevance 0.15
Mast cells immunoreactive to c-kit were also scattered throughout the mucosa (fig 3C,D), and were significantly elevated in the IBS group compared with controls (p?
Positive_regulation (elevated) of c-kit Binding (immunoreactive) of in Mast cells associated with spastic colon
4) Confidence 0.06 Published 2008 Journal Gut Section Body Doc Link PMC2564830 Disease Relevance 0.36 Pain Relevance 0.83

General Comments

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