INT232640

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Context Info
Confidence 0.12
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 4.10
Pain Relevance 0.49

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Jag2)
Anatomy Link Frequency
brain 1
bone marrow 1
Jag2 (Mus musculus)
Pain Link Frequency Relevance Heat
depression 18 97.44 Very High Very High Very High
Pain 22 87.48 High High
headache 6 86.84 High High
Inflammation 6 55.76 Quite High
cytokine 2 45.00 Quite Low
chemokine 2 44.40 Quite Low
abdominal pain 2 29.16 Quite Low
pruritus 18 26.56 Quite Low
nud 2 26.44 Quite Low
Dysuria 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Systemic Mastocytosis 78 100.00 Very High Very High Very High
Cutaneous Mastocytosis 48 99.96 Very High Very High Very High
Mastocytosis 178 98.72 Very High Very High Very High
Depression 18 97.44 Very High Very High Very High
Urticaria Pigmentosa 2 95.72 Very High Very High Very High
Exanthema 2 94.76 High High
Syndrome 8 93.48 High High
Pain 14 87.48 High High
Headache 6 86.84 High High
Amnesia 6 86.20 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our observation that psychological and neurological effects are common in mastocytosis extends earlier findings by Rogers et al. [17], who found that SM is associated with diminished attention and memory, anger, irritability, and depression, a combination of symptoms that they referred to as an “atypical or mixed organic brain syndrome”.
SM Binding (associated) of in brain associated with depression, syndrome, systemic mastocytosis and mastocytosis
1) Confidence 0.12 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2386235 Disease Relevance 1.99 Pain Relevance 0.49
In contrast to CM, SM has a peak onset in adults, tends to be more aggressive, and can involve the skin as well as internal organs and bone marrow.
SM Binding (tends) of in bone marrow associated with cutaneous mastocytosis and systemic mastocytosis
2) Confidence 0.11 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2386235 Disease Relevance 2.11 Pain Relevance 0

General Comments

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