INT232645

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Context Info
Confidence 0.09
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.19
Pain Relevance 1.71

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (INSR) endosome (INSR) plasma membrane (INSR)
nucleus (INSR) carbohydrate metabolic process (INSR)
INSR (Homo sapiens)
Pain Link Frequency Relevance Heat
tramadol 120 100.00 Very High Very High Very High
cINOD 24 96.12 Very High Very High Very High
Pain 48 93.52 High High
Serotonin 6 89.80 High High
opioid receptor 6 87.60 High High
Analgesic 28 85.96 High High
tolerance 9 80.76 Quite High
COX-2 inhibitor 13 77.20 Quite High
antidepressant 41 73.80 Quite High
alcohol 3 70.28 Quite High
Disease Link Frequency Relevance Heat
Insulin Resistance 11 97.00 Very High Very High Very High
Pain 89 93.52 High High
Hemorrhage 2 81.88 Quite High
Impaired Glucose Tolerance 8 80.76 Quite High
Renal Insufficiency 2 69.72 Quite High
Dizziness 4 64.88 Quite High
Vomiting 4 64.00 Quite High
Constipation 4 63.36 Quite High
Toxicity 3 63.20 Quite High
Sleep Disorders 2 61.92 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Immediate-release (IR) tramadol is initiated at 25 mg and titrated in 25 mg increments over 3 days to achieve 25 mg four times daily (qid), then in 50 mg increments over 3 days to 50 mg qid (Ultram PI 2004).
Transcription (initiated) of IR associated with tramadol
1) Confidence 0.09 Published 2007 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2386353 Disease Relevance 0.96 Pain Relevance 1.57
originally described by Matthews et al. in which HOMA-IR (mmol/L ×???
Transcription (described) of HOMA-IR
2) Confidence 0.01 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2872762 Disease Relevance 0.23 Pain Relevance 0.14

General Comments

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