INT232703

Context Info Confidence 0.32 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 2 Disease Relevance 2.18 Pain Relevance 2.00

lipid binding (Bpi) extracellular region (Bpi) cytoplasm (Bpi)

Bpi (Rattus norvegicus)

Pain Link Frequency Relevance Heat Pain 332 99.64 Pain scale 10 97.48 Osteoarthritis 88 80.72 Pain score 12 59.52 cINOD 2 45.28 backache 8 25.36 Cancer pain 16 22.08 phantom limb 4 21.08 Pain management 2 5.00 Arthritis 2 5.00

Disease Link Frequency Relevance Heat Pain 350 99.64 Frailty 118 80.72 Disease 12 75.68 Metastasis 2 55.92 INFLAMMATION 2 44.88 Low Back Pain 8 25.36 Cancer Pain 18 22.08 Arthritis 2 5.00 Cancer 2 5.00 Mental Disorders 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Therefore, a closer association of BPI average pain with WOMAC scores would be expected, and we would put more emphasis on this for the purpose of validation.

BPI Binding (association) of associated with pain

1) Confidence 0.32 Published 2008 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2386464 Disease Relevance 1.04 Pain Relevance 0.90

Moreover, we would expect the association of the BPI scores with the WOMAC scale to be higher than with the Bodily Pain scale of the SF-36, because of the more similar time perspective in the framing of the questionnaire items.

BPI Binding (association) of associated with pain scale

2) Confidence 0.24 Published 2008 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2386464 Disease Relevance 1.14 Pain Relevance 1.10

General Comments

This test has worked.