INT23278

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Context Info
Confidence 0.39
First Reported 1984
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 6
Total Number 6
Disease Relevance 3.54
Pain Relevance 1.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (F13A1) transferase activity, transferring acyl groups (F13A1) cytoplasm (F13A1)
Anatomy Link Frequency
coronary artery 2
F13A1 (Homo sapiens)
Pain Link Frequency Relevance Heat
aspirin 4 99.92 Very High Very High Very High
ischemia 1 96.28 Very High Very High Very High
Angina 13 93.96 High High
metalloproteinase 10 90.64 High High
cva 2 82.36 Quite High
headache 1 77.64 Quite High
epidural 1 40.80 Quite Low
Disease Link Frequency Relevance Heat
Hematoma 4 99.24 Very High Very High Very High
Coronary Artery Disease 2 99.00 Very High Very High Very High
Acute Coronary Syndrome 7 98.84 Very High Very High Very High
Thrombosis 2 96.84 Very High Very High Very High
Cv General 3 Under Development 14 93.96 High High
Coagulation Disorder 1 88.24 High High
Myocardial Infarction 7 87.08 High High
Hemorrhagic Diathesis 3 79.08 Quite High
Headache 1 77.64 Quite High
Paresis 1 76.88 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
[3 operated cases of congenital deficiency of Factor XIII associated with intracranial hematomas].
Negative_regulation (deficiency) of Factor XIII Binding (associated) of associated with hematoma
1) Confidence 0.39 Published 1984 Journal No Shinkei Geka Section Title Doc Link 6504254 Disease Relevance 1.17 Pain Relevance 0.12
Casein zymography revealed an ACP-dependent decrease in fibrin binding of a low molecular weight (Mw) protease triplet (47-, 43-, 42-kDa) and increased fibrin binding of two high Mw proteases (94- and 84-kDa).
Negative_regulation (decrease) of fibrin Binding (binding) of
2) Confidence 0.02 Published 2001 Journal Inflammation Section Abstract Doc Link 11820459 Disease Relevance 0.15 Pain Relevance 0.17
Casein zymography revealed an ACP-dependent decrease in fibrin binding of a low molecular weight (Mw) protease triplet (47-, 43-, 42-kDa) and increased fibrin binding of two high Mw proteases (94- and 84-kDa).
Negative_regulation (decrease) of fibrin Binding (binding) of
3) Confidence 0.02 Published 2001 Journal Inflammation Section Abstract Doc Link 11820459 Disease Relevance 0.15 Pain Relevance 0.16
Fibrin formation and platelet aggregation in patients with severe coronary artery disease: relationship with the degree of myocardial ischemia.
Negative_regulation (aggregation) of Fibrin Binding (formation) of in coronary artery associated with coronary artery disease and ischemia
4) Confidence 0.01 Published 1985 Journal Circulation Section Title Doc Link 2408785 Disease Relevance 0.75 Pain Relevance 0.44
UFH was combined with aspirin to suppress thrombin propagation and fibrin formation in patients presenting with acute coronary syndromes (ACS) or patients undergoing percutaneous coronary intervention (PCI).
Negative_regulation (suppress) of fibrin Binding (formation) of associated with aspirin and acute coronary syndrome
5) Confidence 0.01 Published 2007 Journal Rev Cardiovasc Med Section Abstract Doc Link 17917621 Disease Relevance 0.55 Pain Relevance 0.26
Historically, unfractionated heparin (UFH) has been combined with aspirin to suppress thrombin propagation and fibrin formation; however, its effectiveness has been questioned in this setting.
Negative_regulation (suppress) of fibrin Binding (formation) of associated with aspirin
6) Confidence 0.01 Published 2004 Journal Pharmacotherapy Section Abstract Doc Link 15334859 Disease Relevance 0.76 Pain Relevance 0.22

General Comments

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