INT232787

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.66
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (CYBB, Hif1a) cell differentiation (Hif1a) mitochondrion (CYBB)
protein binding transcription factor activity (Hif1a) DNA binding (Hif1a) signal transducer activity (Hif1a)
Anatomy Link Frequency
endothelial cells 2
CYBB (Homo sapiens)
Hif1a (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 3 84.96 Quite High
Inflammation 11 84.56 Quite High
analgesia 1 40.00 Quite Low
Inflammatory response 7 5.00 Very Low Very Low Very Low
Tetrahydrobiopterin 4 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
cva 2 5.00 Very Low Very Low Very Low
Inflammatory stimuli 1 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypoxia 2 100.00 Very High Very High Very High
Sepsis 45 87.20 High High
Coagulation Disorder 2 86.80 High High
INFLAMMATION 20 84.56 Quite High
Infection 4 53.20 Quite High
Adhesions 3 42.72 Quite Low
Sleep Disorders 1 40.96 Quite Low
Stress 7 5.00 Very Low Very Low Very Low
Systemic Inflammatory Response Syndrome 7 5.00 Very Low Very Low Very Low
Death 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
NADPH oxidase-derived oxidants also stimulate the activation of the heterodimeric transcription factor hypoxia inducible factor-1 (HIF-1) in endothelial cells [61].
NADPH oxidase Positive_regulation (stimulate) of Positive_regulation (activation) of HIF-1 in endothelial cells associated with hypoxia
1) Confidence 0.01 Published 2008 Journal Journal of Clinical Biochemistry and Nutrition Section Body Doc Link PMC2386519 Disease Relevance 0.66 Pain Relevance 0.12

General Comments

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