INT232793

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Context Info
Confidence 0.31
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 7
Disease Relevance 3.90
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Pgc) extracellular region (Pgc) nucleolus (Pgc)
nucleus (Pgc)
Anatomy Link Frequency
myotubes 1
chief cells 1
Pgc (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 36 75.32 Quite High
addiction 12 75.00 Quite High
Inflammation 16 69.92 Quite High
Somatostatin 2 21.76 Low Low
ischemia 6 5.00 Very Low Very Low Very Low
Paracetamol 6 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
adenocard 1 5.00 Very Low Very Low Very Low
peptic ulcer disease 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Shock 906 95.48 Very High Very High Very High
Aging 6 92.16 High High
Diabetes Mellitus 6 90.64 High High
Stress 138 89.44 High High
Sprains And Strains 66 87.32 High High
Liver Cancer 12 86.72 High High
INFLAMMATION 15 69.92 Quite High
Alzheimer's Dementia 6 27.08 Quite Low
Hyperplasia 6 13.04 Low Low
Achlorhydria 1 6.32 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Overproduction of PGC-1?
Gene_expression (Overproduction) of PGC
1) Confidence 0.31 Published 2010 Journal BMC Genomics Section Body Doc Link PMC2823686 Disease Relevance 0.08 Pain Relevance 0.03
Co-activator 1 (PGC-1) family which includes PGC-1?
Gene_expression (includes) of PGC
2) Confidence 0.31 Published 2010 Journal BMC Genomics Section Body Doc Link PMC2823686 Disease Relevance 0.64 Pain Relevance 0
-null mice with WY prevented the down-regulation of these genes possibly through the increased expression of PGC-1?
Gene_expression (expression) of PGC
3) Confidence 0.31 Published 2010 Journal BMC Genomics Section Body Doc Link PMC2823686 Disease Relevance 0.98 Pain Relevance 0
-null mice with WY increased expression of PGC-1?
Gene_expression (expression) of PGC
4) Confidence 0.28 Published 2010 Journal BMC Genomics Section Abstract Doc Link PMC2823686 Disease Relevance 1.34 Pain Relevance 0.08
Co-activator 1 (PGC-1) family which includes PGC-1?
Gene_expression (includes) of PGC
5) Confidence 0.27 Published 2010 Journal BMC Genomics Section Body Doc Link PMC2823686 Disease Relevance 0.63 Pain Relevance 0
leads to increases in mitochondrial volume density in C2C12 myotubes [58], and defects in PGC-1?
Gene_expression (defects) of PGC in myotubes
6) Confidence 0.27 Published 2010 Journal BMC Genomics Section Body Doc Link PMC2823686 Disease Relevance 0.09 Pain Relevance 0.03
Kakei et al. [24] reported that 4 weeks treatment with omeprazole induced a marked decrease in the number of chief cells in the gastric mucosa with a concomitant increase in the number of immature pepsinogen-producing cells expressing class III mucin.
Gene_expression (producing) of pepsinogen in chief cells
7) Confidence 0.01 Published 2008 Journal Journal of Clinical Biochemistry and Nutrition Section Body Doc Link PMC2386521 Disease Relevance 0.13 Pain Relevance 0.07

General Comments

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