INT232837

Context Info Confidence 0.50 First Reported 2008 Last Reported 2008 Negated 0 Speculated 2 Reported most in Body Documents 1 Total Number 2 Disease Relevance 1.57 Pain Relevance 0

structural molecule activity (Krt18) microtubule organizing center (Krt18) cytoplasm (Krt18)

Krt18 (Mus musculus)

Pain Link Frequency Relevance Heat fibrosis 16 5.00 Paracetamol 8 5.00 Bile 6 5.00 Inflammation 6 5.00 alcohol 6 5.00 Potency 2 5.00

Disease Link Frequency Relevance Heat Nash(non-alcoholic Steatohepatitis) 14 94.44 Parkinson's Disease 2 93.40 Stress 36 89.08 Hepatotoxicity 4 87.36 Targeted Disruption 28 79.60 Aging 4 67.44 Apoptosis 46 5.00 Disease 34 5.00 Liver Disease 30 5.00 Acute Liver Failure 18 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Keratins are major constituents of MDBs and both altered K8/K18 expression and keratin modification seems to affect MDB formation (Zatloukal et al. 2007; Ku et al. 2007).

Spec (seems) Regulation (altered) of Gene_expression (expression) of K18

1) Confidence 0.50 Published 2008 Journal Histochem Cell Biol Section Body Doc Link PMC2386529 Disease Relevance 0.78 Pain Relevance 0

Keratins are major constituents of MDBs and both altered K8/K18 expression and keratin modification seems to affect MDB formation (Zatloukal et al. 2007; Ku et al. 2007).

Spec (seems) Regulation (affect) of Gene_expression (expression) of K18

2) Confidence 0.37 Published 2008 Journal Histochem Cell Biol Section Body Doc Link PMC2386529 Disease Relevance 0.79 Pain Relevance 0

General Comments

This test has worked.