INT232851

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Context Info
Confidence 0.32
First Reported 2008
Last Reported 2008
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.47
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

structural molecule activity (Krt8) nucleus (Krt8) cytoplasm (Krt8)
Krt8 (Mus musculus)
Pain Link Frequency Relevance Heat
Kinase C 13 5.00 Very Low Very Low Very Low
fibrosis 8 5.00 Very Low Very Low Very Low
metalloproteinase 6 5.00 Very Low Very Low Very Low
agonist 5 5.00 Very Low Very Low Very Low
Paracetamol 4 5.00 Very Low Very Low Very Low
Inflammation 3 5.00 Very Low Very Low Very Low
alcohol 3 5.00 Very Low Very Low Very Low
Bile 3 5.00 Very Low Very Low Very Low
corticosteroid 2 5.00 Very Low Very Low Very Low
addiction 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Acantholysis 65 79.52 Quite High
Bullous Skin Disease 304 78.52 Quite High
Targeted Disruption 14 78.08 Quite High
Shock 3 56.88 Quite High
Aging 2 49.60 Quite Low
Mucocutaneous Lymph Node Syndrome 1 34.00 Quite Low
Nash(non-alcoholic Steatohepatitis) 7 24.92 Low Low
Adhesions 51 24.08 Low Low
Parkinson's Disease 1 23.88 Low Low
Blister 12 20.72 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Alternatively, K8 hyperphosphorylation may induce MDB formation through inhibition of K8 degradation, which results in increased K8/K18 ratio (Ku and Omary 2000).
Spec (may) Positive_regulation (induce) of Phosphorylation (hyperphosphorylation) of K8
1) Confidence 0.32 Published 2008 Journal Histochem Cell Biol Section Body Doc Link PMC2386529 Disease Relevance 0.13 Pain Relevance 0
It has been shown recently that serine phosphorylation of cytokeratin 8 by p38MAPK induced cytokeratin network disassembly (Woll et al. 2007).
Positive_regulation (induced) of Phosphorylation (phosphorylation) of cytokeratin 8
2) Confidence 0.03 Published 2008 Journal Histochem Cell Biol Section Body Doc Link PMC2413110 Disease Relevance 0.34 Pain Relevance 0

General Comments

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