INT232900

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Context Info
Confidence 0.03
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.49
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (ABR) structural molecule activity (Krt8) nucleus (Krt8)
plasma membrane (ABR) cytoplasm (Krt8)
ABR (Homo sapiens)
Krt8 (Mus musculus)
Pain Link Frequency Relevance Heat
alcohol 6 64.80 Quite High
fibrosis 16 5.00 Very Low Very Low Very Low
Paracetamol 8 5.00 Very Low Very Low Very Low
Bile 6 5.00 Very Low Very Low Very Low
Inflammation 6 5.00 Very Low Very Low Very Low
Potency 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 28 87.92 High High
Aging 4 79.36 Quite High
Nash(non-alcoholic Steatohepatitis) 14 54.68 Quite High
Parkinson's Disease 2 53.64 Quite High
Stress 36 49.32 Quite Low
Hepatotoxicity 4 47.60 Quite Low
Alcoholic Liver Diseases 2 11.52 Low Low
Apoptosis 46 5.00 Very Low Very Low Very Low
Disease 34 5.00 Very Low Very Low Very Low
Liver Disease 30 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, autophagic degradation is upregulated in DDC-fed mice and its further stimulation with rapamycin attenuates spontaneous MDB formation in K8 overexpressing mice (Harada et al. 2008).
MDB Binding (formation) of K8
1) Confidence 0.03 Published 2008 Journal Histochem Cell Biol Section Body Doc Link PMC2386529 Disease Relevance 0.14 Pain Relevance 0.03
Among posttranslational modifications, MDB formation is associated with K8 hyperphosphorylation and transamidation (Zatloukal et al. 1992; Stumptner et al. 2000).
MDB Binding (associated) of K8
2) Confidence 0.03 Published 2008 Journal Histochem Cell Biol Section Body Doc Link PMC2386529 Disease Relevance 0.35 Pain Relevance 0

General Comments

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