INT232917

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Context Info
Confidence 0.16
First Reported 2006
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.04
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (KRT8) structural molecule activity (KRT8) nucleus (KRT8)
cytoskeleton organization (KRT8) cytoplasm (KRT8)
Anatomy Link Frequency
intestinal epithelium 1
KRT8 (Homo sapiens)
KRT19 (Homo sapiens)
Pain Link Frequency Relevance Heat
Bile 1 94.76 High High
aspirin 44 71.12 Quite High
Inflammation 14 5.00 Very Low Very Low Very Low
medulla 7 5.00 Very Low Very Low Very Low
cINOD 4 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
Chronic pancreatitis 1 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Paracetamol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Lung Cancer 6 81.08 Quite High
Cancer 85 78.80 Quite High
Carcinoma 22 77.72 Quite High
Asthma 60 76.36 Quite High
Apoptosis 18 75.08 Quite High
Necrosis 2 74.52 Quite High
Chronic Sinusitis 2 66.40 Quite High
Disease 16 45.92 Quite Low
Breast Cancer 11 39.12 Quite Low
Skin Cancer 29 34.84 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, in several epithelia lacking K7 such as intestinal epithelium, the type I keratin K19 must form a pair with the sole type II keratin K8.
keratin K8 Binding (pair) of keratin K19 in intestinal epithelium
1) Confidence 0.16 Published 2008 Journal Histochem Cell Biol Section Body Doc Link PMC2386534 Disease Relevance 0.62 Pain Relevance 0.05
IgG antibodies to CK19 were significantly associated with IgG to CK8 (Pearson's coefficient=0.320, p<0.001) and CK18 (Pearson's coefficient=0.442, p<0.001).


CK8 Binding (associated) of CK19
2) Confidence 0.09 Published 2006 Journal Journal of Korean Medical Science Section Body Doc Link PMC2729943 Disease Relevance 0.42 Pain Relevance 0.04

General Comments

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