INT232970

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Context Info
Confidence 0.41
First Reported 2006
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 6
Disease Relevance 3.41
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
lung 1
KRT19 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 30 91.60 High High
chemokine 7 89.12 High High
aspirin 132 81.68 Quite High
Paracetamol 3 70.64 Quite High
cINOD 12 5.00 Very Low Very Low Very Low
medulla 7 5.00 Very Low Very Low Very Low
imagery 4 5.00 Very Low Very Low Very Low
corticosteroid 3 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
fibrosis 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pancreatic Cancer 1 99.44 Very High Very High Very High
Breast Cancer 83 98.86 Very High Very High Very High
Cancer 223 97.30 Very High Very High Very High
Advanced Or Metastatic Breast Cancer 18 95.16 Very High Very High Very High
Metastasis 52 94.96 High High
Asthma 180 94.76 High High
INFLAMMATION 32 91.60 High High
Apoptosis 38 84.32 Quite High
Malignant Neoplastic Disease 8 62.32 Quite High
Chronic Sinusitis 6 60.64 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Examples of very recent new developments in tumor classification are the recognition of the basal-like subtype of breast cancer on the basis of the expression of K5 and the prognostic relevance of K19 in endocrine pancreatic tumors.
Localization (relevance) of K19 associated with cancer, pancreatic cancer and breast cancer
1) Confidence 0.41 Published 2008 Journal Histochem Cell Biol Section Body Doc Link PMC2386534 Disease Relevance 0.77 Pain Relevance 0
Moreover, the enumeration of both MUC1-and CK19-secreting cells allowed the detection of viable DTCs in the BM of 90% and 54% of breast cancer patients with and without overt distant metastasis, respectively [42].
Localization (-) of CK19 associated with breast cancer and metastasis
2) Confidence 0.37 Published 2008 Journal Breast Cancer Res Section Body Doc Link PMC2605098 Disease Relevance 0.67 Pain Relevance 0
Moreover, the enumeration of both MUC1-and CK19-secreting cells allowed the detection of viable DTCs in the BM of 90% and 54% of breast cancer patients with and without overt distant metastasis, respectively [42].
Localization (secreting) of CK19 associated with breast cancer and metastasis
3) Confidence 0.37 Published 2008 Journal Breast Cancer Res Section Body Doc Link PMC2605098 Disease Relevance 0.67 Pain Relevance 0
IgG immunoblotting for CK8, CK18, and CK19
Localization (immunoblotting) of CK19
4) Confidence 0.37 Published 2006 Journal Journal of Korean Medical Science Section Body Doc Link PMC2729943 Disease Relevance 0 Pain Relevance 0
IgG immunoblotting for CK8, CK18, and CK19
Localization (immunoblotting) of CK19
5) Confidence 0.37 Published 2006 Journal Journal of Korean Medical Science Section Body Doc Link PMC2729943 Disease Relevance 0.42 Pain Relevance 0.04
Thus, CK8, CK18, and CK19, which were used in this study, have been found only in simple epithelia, including both bronchial and lung alveolar epithelial cells (17), which are the major target tissues of asthma.
Localization (found) of CK19 in lung associated with asthma
6) Confidence 0.37 Published 2006 Journal Journal of Korean Medical Science Section Body Doc Link PMC2729943 Disease Relevance 0.89 Pain Relevance 0.19

General Comments

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